迭代重建技术在HRCT低剂量下诊断肺磨玻璃密度结节的可行性应用

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Abstract Objective To evaluate the feasibility of diagnosing pulmonary grinded glass nodule (pGGN) by different levels of iDose4 iterative reconstruction technology under low HRCT conditions. Methods Selected 40 cases of patients who was diagnosed as a glass-polluted nodule by conventional chest CT examination in Traditional Chinese Medicine Hospital of Pinghu City, from October 1 2014 to April 1 2016. 16-slice spiral CT was performed on 40 pulmonary nodular nodules whose diameter were 5 to 13 mm, took four different dose conditions (tube voltage 120 kV; tube current 100, 50, 25, 10 mAs), reconstructed all the data by iDose4 iteration reconstruction techniques and traditional filtered backprojection (FBP). Two experienced physicians were asked to evaluate images at different dose levels and different reconstruction techniques. Consistency assessment was conducted by Kappa analysis, and the image noise (MSD) and effective radiation dose (ED) was measured for each examination. Results The difference was statistically significant (P < 0.05) in SD values under different tube currents and image reconstruction techniques. The difference was statistically significant (P < 0.05) in SD values under the same tube current conditions and different reconstruction techniques. There was no significant difference(P > 0.05) in CT values of lung parenchyma under different tube currents and image reconstruction techniques. The consistency was good(Kappa=0.601, P = 0.000) between the two doctors, under traditional FBP and iDose4 technology, there was a statistically significant difference (P < 0.05) in the comparison of the visibility of pGGN at 100, 50, 25, 10 mAs. Under the condition of 50, 25, 10 mAs, there was a statistically significant difference (P < 0.05) in the number of nodules on the high score under the iDose4-4/7 reconstruction technique. Conclusion 16-slice spiral CT can be used to detect lung-dense glass nodules at 10 mAs, it can ensure images in the clinical combine with iDose4 iterative reconstruction technology. The radiation dose to the patient can be further reduced, and it is worthy of clinical promotion in early lung cancer screening.

Key words： Iterative reconstruction technique Filtered backprojection Lung grinding glass density Radiation dose

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	LIU Wenhui1 CAO Liming1 LI Liangshan2▲ LI Bin2

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LIU Wenhui1 CAO Liming1 LI Liangshan2▲ LI Bin2. Feasibility of low - dose HRCT in the diagnosis of pulmonary - ground - glass - density nodules using iterative reconstruction[J]. 中国医药导报, 2018, 15(16): 118-121,129.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I16/118

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