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| Screening results of human papillomavirus in asymptomatic women of childbearing age and analysis of risk factors for infection |
| ZHU Li LIU Qin |
| Huizhou Maternal and Child Health and Family Planning Service Center (Formerly Huizhou First Maternal and Child Health Hospital), Guangdong Province, Huizhou 516001, China |
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Abstract Objective To investigate the screening results of human papillomavirus (HPV) in asymptomatic women of childbearing age and the risk factors of infection. Methods A total of 924 asymptomatic women of childbearing age from June to December 2017 in Huizhou Maternal and Child Health and Family Planning Service Center were selected. All subjects were investigated for general condition and HPV infection. Results among 924 subjects, 112 cases were positive for HPV infection and 172 HPV subtypes were infected. The positive rate was 12.12%. Univariate analysis showed that age, smoking history, drinking history, times of pregnancy were not influencing factors of HPV infection (P > 0.05). The education, time of first sexual life, history of abortion, parity, contraceptive method, number of sexual partners, frequency of sexual life, prepuce length of sexual partners were the influencing factors of HPV infection in women of childbearing age (P < 0.05). The results of multivariate Logistic analysis showed that the number of sexual partners was more than 2 (OR=3.902, 95%CI: 1.744-12.690, P < 0.01）, long prepuce of sexual partners (OR=2.770, 95%CI: 1.410-6.472, P < 0.01) were an independent risk factor for HPV infection in women of childbearing age. Condom contraception was the protective factor of HPV infection in women of childbearing age (OR=0.627, 95%CI: 0.389-0.856, P < 0.01). Conclusion There is no symptomatic childbearing age in this area. The infection rate of HPV52, HPV16, HPV58 is a common high risk subtype of HPV58, and the number of sexual partners is more than 2. Sexual partners with long foreskin were independent risk factors for HPV infection in women of childbearing age, condom contraception was the protective factor of HPV infection in women of childbearing age, and clinical monitoring should be strengthened for women with risk factors.
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