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| Effects of autologous blood transfusion on maternal coagulation function, hemodynamics and liver and kidney function in Department of Obstetrics |
| ZHAO Qingzhen1 SUN Jing2 XIONG Xuguang2 HU Chaofeng2 LI Ping3.▲ |
1.Department of Anesthesiology, Affiliated Hospital of Ningbo University, Zhejiang Province, Ningbo 315200;
2.Department of Gynaecology and Obstetrics, the Second Hospital of Yinzhou District, Zhejiang Province, Ningbo 315100, China;
3.Departmentof Anesthesiology, Second Hospital of Yinzhou District, Zhejiang Province, Ningbo 315100, China |
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Abstract Objective To investigate the effect of blood transfusion on maternal coagulation function, hemodynamics and liver and kidney function in Department of Obstetrics. Methods A total of 150 patients with major obstetric hemorrhage from April 2015 to May 2016 in the Affiliated Hospital of Ningbo University and the Second Hospital of Yinzhou District of Ningbo City were selected and divided into control group (75 cases) and experimental group (75 cases) by a random number table method. Allogeneic blood transfusions and autologous blood transfusions were applied respectively. The differences of coagulation function (APTT, PT), electrolytes (K, Na, Cl and pH), hemodynamics [mean arterial pressure (MAP), heart rate (HR)] and liver and kidney function [aspartate aminotransferase (AST), alanine aminotransferase (ALT), urine creatinine (Cr), blood urea nitrogen (BUN)] were analyzed between the two groups before and after transfusion. Results Compared with pretransfusion, the levels of PT, APTT, serum potassium, sodium, chloride, pH, MAP, and HR were significantly changed in the two groups after transfusion, and the differences were statistically significant (P < 0.05). There was no significant change in the levels of AST, ALT, Cr and BUN before and after the study (P > 0.05). Compared with the experimental group, the levels of PT, APTT, serum chloride, pH, MAP and HR in the control group were changed more obviously, and the differences were statistically significant (P < 0.05). Conclusion Autologous blood transfusion is more safer and effective in patients with obstetric hemorrhage, and it is worthy of being widely used in clinical practice.
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