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| Analysis of HPV infection status of rural females from parts of Jiangsu area |
| ZHOU Qing JIANG Zhixin WANG Lijuan SHI Hui LIN Ning WU Yulin XU Haoqin |
| Jiangsu Institute of Planned Parenthood Research, Jiangsu Clinical Laboratory of Reproductive Health, Jiangsu Province, Nanjing 210036, China |
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Abstract Objective To understand the infection status of human papilloma virus (HPV) of partial rural females in Jiangsu Province in order to prevent and reduce HPV infection and improve female health level. Methods A total of 401 rural women from Tongshan, Sheyang, Taixing, Gaoyou, Xinghua and Suyu from January to May 2015 were selected, and divided into 4 groups, normal/inflammation group, CIN1 group, CIN2 group and CIN3 group respectively. HPV DNA genotypes were detected and analyzed by genetic chip method. Results One hundred and twenty-five samples were found positive of HPV in 387 samples (eligible) among 401 samples. and the positive rate of HPV was 32.30%. The HPV-positive rates in normal/inflammatory, CIN1, CIN2 and CIN3 groups were 32.04%, 25.74%, 35.16% and 36.96% respectively. The total positive rate of high-risk HPV was 23.51%, and those rates in normal/inflammatory, CIN1, CIN2 and CIN3 groups were 18.45%, 19.80%, 28.57% and 28.26% respectively. There was no statistical difference among the 4 groups (P > 0.05). The top three subtypes were HPV16, HPV58 and HPV18. Conclusion The high-risk HPV infection rate of rural females is high. It is important to enhance HPV screening and HPV vaccination to prevent and reduce cervical cancer.
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