彩色多普勒超声及内膜微血管密度在反复自然流产患者子宫内膜容受性评价中的应用

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Abstract Objective To discuss on the application value of color Doppler ultrasound and MVD in the evaluation diagnostic of recurrent spontaneous abortion in patients with endometrial receptivit. Methods From December 2016 to December 2017, 61 cases of recurrent spontaneous abortion as the object in Maternal and Child Health Hospital of Wenling were selected and divided into pregnancy group (n = 25) and non-pregnancy group (n = 36) according to whether had pregnancy. All the patients underwent color doppler ultrasound examination and endometrial biopsy, endometrial blood flow distribution, hemodynamic parameters and endometrial microvessel density (MVD) between the two groups were compared. Results There were no significant differences in age, abortion frequency, BMI and estrogen levels between the two groups (t = 0.382, 0.257, 0.644, 0.152, 0.243, all P > 0.05). There were no significant difference in the endometrial thickness, endometrial volume, uterine artery PI, RI and S/D indexes (t = 0.416, 0.117, 0.416, 1.046, 0.240, all P > 0.05), but the levels of PI, RI and S/D in uterine spiral blood were significantly higher than the non-pregnant group (t = 2.927, 3.062, 4.195, all P < 0.05). There was statistically significant in the average MVD between two groups (t = 8.515, P < 0.05). Conclusion There is a certain clinical value in evaluating endometrial receptivity in patients with recurrent spontaneous abortion by transvaginal color doppler ultrasonography, they can predict the patients′ pregnancy outcome through the detection of helical artery blood flow parameters, can provide guidance for clinical treatment for patients with recurrent spontaneous abortion by endometrial examination.

Key words： Color Doppler ultrasound Recurrent spontaneous abortion Endometrial receptivity Microvessel density Application value

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	ZOU Shuwei1 HAN Yanfeng2 WU Xiuying1▲

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ZOU Shuwei1 HAN Yanfeng2 WU Xiuying1▲. Study on the application value of color Doppler ultrasound and MVD in the evaluation diagnostic of recurrent spontaneous abortion in patients with endometrial receptivit[J]. 中国医药导报, 2018, 15(14): 54-57.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I14/54

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