奥施康定联合即释吗啡片治疗癌痛的效果及对患者生存质量的影响

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Abstract Objective To analysis of Oxycontin combined with Morphine Tablets in treatment of cancer pain and its effect on the quality of life of patients. Methods From August 2016 to September 2017 in Qianjiang Central Hospital of Chongqing, 100 patients with cancer pain were randomly divided into observation group and control group, with 50 patients in each group. The control group was treated with Oxycontin, the observation group was treated with Oxycontin combined with Morphine Tablets. Before and after treatment, the visual analogue score （VAS） was used in the assessment of the clinical efficacy in the treatment of patients, the QLQ-C30 scale was used to evaluate the life quality of the patients, the ECOG-PS physical status scale was used for patients′ physical condition evaluation, statistical analysis of the clinical curative effect and adverse reactions of patients was carried out. Results There was no significant difference between the two groups of visual analogue score （VAS）, QLQ-C30 and ECOC-PS before treatment （P > 0.05）. The scores of VAS, QLQ-C30 and ECOC-PS in the two groups were significantly improved after treatment （P < 0.05）, and the VAS, QLQ-C30 and ECOC-PS scores of the patients after treatment in the observation group were significantly better than those of the control group （P < 0.05）. The analgesic efficacy of the observation group was significantly higher than that of the control group （P < 0.05）, and the incidence of nausea, vomiting, dizziness, constipation and dysuria was significantly lower in the observation group than that in the control group （P < 0.05）. Conclusion The Oxycontin combined with Morphine Tablets for the treatment of cancer pain patients can alleviate the pain symptoms of patients, and effectively improve the quality of life of patients, has high clinical application value.

Key words： Oxycontin Morphine Tablets Cancer pain Quality of life

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	SONG Jianming1 LI Bin2▲

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SONG Jianming1 LI Bin2▲. Oxycontin combined with Morphine Tablets in the treatment of cancer pain and its effect on the quality of life of patients[J]. 中国医药导报, 2018, 15(13): 89-92.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I13/89

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