女性打鼾人群阻塞性睡眠呼吸暂停低通气综合征筛查模型的初步研究

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Abstract Objective To investigate the obstructive sleep apnea hypopnea syndrome (OSAHS) screening model for female snorers. Methods The clinical data of 223 female snorers, that had conducted sleep monitor in Peking Union Medical College Hospital from January 2017 to February 2018, was analyzed to investigate the risk factors of OSAHS and snoring conditions. According to the Logistic regression coefficient, the indices were assigned, a screening model was established, the score of the screening model was calculated and the ROC curve was plotted to evaluate the screening effect. Results There were 110 females diagnosed with OSAHS and the other 113 females were not. There were statistically significant significance in the body mass index (BMI), menstrual status, modified Mallampati index (MMP), number of year of snoring and degree of snoring categorized into Logistic regression equation model (P ＜ 0.05). The indices were assigned as BMI ≥ 24.55 kg/m2 (3 points), menopause (3 points), MMP ≥ Ⅲ class (2 points), year of snoring ≥ 10.25 years (4 points), degree of snoring was severe (2 points). The screening model score ranged from 0 to 14 points, the area under the ROC curve A was 0.795, the 95% confidence interval was (0.737, 0.853), which had significant difference (P ＜ 0.001). When the score got 7 points, Youden index was 0.452 the maximum, so 7 points were taken as the best division point. When screening model in this study set apnea hypopnea index (AHI) ≥ 5 times/h as standard of diagnosis, the sensitivity, specificity, positive predictive value, and negative predictive value were 70.9%, 74.3%, 72.6% and 71.8%. Conclusion Through this research of risk factors of OSAHS and snoring conditions of female snorers, the OSAHS screening model of female snorers is constructed, which has a certain clinical application value.

Key words： Female Snoring Obstructive sleep apnea hypopnea syndrome Screening model

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	BU Mengying1 HUANG Rong2 XIAO Yi2 LUO Jinmei2 YU Lijun1

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BU Mengying1 HUANG Rong2 XIAO Yi2 LUO Jinmei2 YU Lijun1. Preliminary study of the obstructive sleep apnea hypopnea syndrome screening model for female snorers[J]. 中国医药导报, 2018, 15(12): 167-171.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I12/167

[1] Epstein LJ，Kristo D，Jr SP，et al. Clinical guideline for the evaluation，management and long-term care of obstructive sleep apnea in adults [J]. JCSM，2009，5（3）：263-276.
[2] Da SKV，Garcia RML，Lagoeiro JAJ，et al. Prevalence of Risk for Obstructive Sleep Apnea Syndrome and Association With Risk Factors in Primary Care [J]. Arq Brasil Card，2016，106（6）：474-480.
[3] Young T，Evans L，Finn L，et al. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women [J]. Sleep，1997，20（9）：705-706.
[4] Pataka A，Daskalopoulou E，Kalamaras G，et al. Evaluation of five different questionnaires for assessing sleep apnea syndrome in a sleep clinic [J]. Sleep Med，2014，15（7）：776-781.
[5] 杜丽娜，李哲，唐向东.四种量表在阻塞性睡眠呼吸暂停综合征筛查中的应用价值[J].中华医学杂志，2015，95（42）：3407-3410.
[6] Silva S，Abeyratne UR，Hukins C. Impact of gender on snore-based obstructive sleep apnea screening [J]. Physiol Meas，2012，33（4）：587-601.
[7] 中华医学会呼吸病学分会睡眠呼吸障碍学组.阻塞性睡眠呼吸暂停低通气综合征诊治指南（2011年修订版）[J].中华结核和呼吸杂志，2012，35（1）：9-12.
[8] Friedman M，Tanyeri H，La RM，et al. Clinical predictors of obstructive sleep apnea [J]. Laryngoscope，1999，109（12）：1901-1907.
[9] Young T，Peppard PE，Gottlieb DJ. Epidemiology of obstructive sleep apnea：a population health perspective [J]. Am J Respir Crit Care Med，2002，165（9）：1217-1239.
[10] Sean H，Shyam S，Jerry A，et al. Body Mass Index，Gender，and Ethnic Variations Alter the Clinical Implications of the Epworth Sleepiness Scale in Patients with Suspected Obstructive Sleep Apnea [J]. Open Respir Med J，2012，6：20-27.
[11] Lim YH，Choi J，Kim KR，et al. Sex-Specific Characteristics of Anthropometry in Patients With Obstructive Sleep Apnea：Neck Circumference and Waist-Hip Ratio [J]. Ann Oto Rhinol Laryn，2014，123（7）：517-523.
[12] Mohsenin V. Gender differences in the expression of sleep-disordered breathing：role of upper airway dimensions [J]. Chest，2001，120（5）：1442-1447.
[13] Rowley JA，Sanders CS，Zahn BR，et al. Gender differences in upper airway compliance during NREM sleep：role of neck circumference [J]. J Appl Physiol，2002，92（6）：2535-2541.
[14] Young T，Finn L，Austin D，et al. Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study [J]. Am J Resp Crit Care Med，2003，167（9）：1181-1185.
[15] Block AJ，Wynne JW，Boysen PG. Sleep-disordered breathing and nocturnal oxygen desaturation in postmenopausal women [J]. Am J Med，1980，69（1）：75-79.
[16] Mirer AG，Young T，Palta M，et al. Sleep-disordered breathing and the menopausal transition among participants in the Sleep in Midlife Women Study [J]. Menopause（New York, N.Y.），2015，24（2）：157-162.
[17] Bixler EO，Vgontzas AN，Lin HM，et al. Prevalence of sleep-disorderd breathing in women：effects of gender [J]. Am J Crit Care Med，2001，163（3）：608-613.
[18] Boynton G，Vahabzadeh A，Hammoud S，et al. Validation of the STOP-BANG Questionnaire among Patients Referred for Suspected Obstructive Sleep Apnea [J]. J Sleep Disord Treat Care，2013，2（4）.doi：10.4172/2325-9639. 1000121.
[19] 潘凤锦，刘建红，谢宇萍，等.广西地区中年打鼾者简单三参数筛查OSAHS的多中心研究[J].中华医学杂志，2015，95（2）：100-105.
[20] 宋玮，蒋丽君，刘建红，等.颈围对阻塞性睡眠呼吸暂停低通气综合征筛查作用的研究[J].中国临床新医学，2012， 5（11）：1026-1030.