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Prognosis evaluation of patients with idiopathic sensorineural hearing loss by hyperglycemia |
CHEN Xianglei ZHANG Nianwu ZHAO Dan LIU Shuai |
Department of Otolaryngology, Rizhao Hospital of TCM, Shandong Province, Rizhao 276800, China |
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Abstract Objective To evaluate the prognostic value of hyperglycemia in patients with idiopathic sensorineural hearing loss (ISSHL). Methods From June 2015 to August 2017, 94 patients with ISSHL treated at Department of Otolaryngology, Rizhao Hospital of TCM were selected and divided into normal glucose tolerance group (45 cases), prediabetes group (28 cases) and diabetes mellitus group (21 cases) according to the results of glucose tolerance test and glycosylated hemoglobin level test. Before and after treatment, they were tested by pure tone audiometry examination to compare the hearing recovery of the three groups. Results The rate of hearing recovery in normal glucose tolerance group was higher than that the in prediabetes group and diabetes mellitus group (P < 0.05). There was no statistically significant difference in the rate of hearing recovery between the in prediabetes group and diabetes mellitus group (P > 0.05). Conclusion Hyperglycemia can affect the prognosis of patients with ISSHL, which can be used as an index for evaluating the rehabilitation of patients with ISSHL.
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[1] 王欣.尿酸与突发性耳聋关系研究及影响突发性耳聋预后的相关因素初步探讨[D].石家庄:河北医科大学,2016.
[2] 陈宏,齐国荣,张学艳,等.心理状态及微循环障碍与突发性耳聋的相关性研究[J].山西医药杂志,2016,45(8):953-955.
[3] 孟岩,吴小娟,李然,等.糖尿病前期患者听力损失特点分析[J].安徽医科大学学报,2016,51(10):1481-1485.
[4] 中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳鼻咽喉头颈外科学分会.突发性聋诊断和治疗指南(2015)[J].中华耳鼻咽喉头颈外科杂志,2015,50(6):443-447.
[5] Wang CT,Huang TW,Kuo SW,et al. Correlation between audiovestibular function tests and hearing outcomes in severe to profound sudden sensorineural hearing loss [J]. Ear Hear,2009,30:110-114.
[6] Hikita-Watanabe N,Kitahara T,Horri A,et al. Tinnitus as a prognostic factor of sudden deafness [J]. Acta Otolaryngol,2010,130:79-83.
[7] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中华糖尿病杂志,2014,6(7):447-498.
[8] 陈肇臻.鼓室内注射地塞米松治疗突发性耳聋的临床疗效观察[J].现代诊断与治疗,2015,26(15):3478-3479.
[9] 黄国威,吕萍,于宁.糖尿病性听力损失的特点及发生机制[J].听力学及言语疾病杂志,2016,24(6):624-627.
[10] 梁华,钟时勋.突发性聋患者血脂及血液流变学变化研究[J].国际耳鼻咽喉头颈外科杂志,2016,40(6):338-341.
[11] Lim HJ,Kim YT,Choi SJ,et al. Efficacy of 3 different steroid treatments for sudden sensorineural hearing loss:a prospective,randomized trial [J]. Otolaryngol Head Neck Surg,2013,148:121-127.
[12] Nagaoka J,Anjos MF,Takata TT,et al. Idiopathic sudden sensorineural hearing loss:evolution in the presence of hypertension,diabetes mellitus and dyslipidemias [J]. Braz J Otorhinolaryngol,2010,76:363-369.
[13] 刘文,黄晓悫.鼓室内注入类固醇激素治疗伴糖尿病的突发性聋Meta分析[J].中国耳鼻咽喉头颈外科,2017, 24(6):291-295.
[14] 张武宁.糖皮质激素治疗突发性耳聋的作用机制[J].医学综述,2013,19(14):2513-2517.
[15] 管红霞,张志坚,江洋,等.糖皮质激素治疗突发性聋的研究进展[J].中国医药导报,2016,13(5):41-45.
[16] 刘璐,钟时勋.糖皮质激素鼓室给药治疗突发性聋的现况分析[J].中华耳科学杂志,2015,13(1):176-178.
[17] 李晖,刘莉,李俊.两种糖皮质激素鼓室注射治疗突发性聋的疗效比较[J].听力学及言语疾病杂志,2014,22(4):417-418.
[18] Costa PZ,Soares R. Neovascularization in diabetes and its complication. Unraveling the angiogenic paradox [J]. Life Sci,2013,92:1037-1045.
[19] 胡雯,薛希均.影响突发性聋预后的研究进展[J].医学综述,2015,22(14):2583-2584.
[20] 胡焱,黄庆琳,傅江涛,等.耳后与鼓室注射甲强龙治疗难治性突发性耳聋的疗效及对血糖的影响[J].现代实用医药,2017,29(4):523-525.
[21] 李琦,欧阳天斌.伴与不伴2型糖尿病突发性聋听力受损情况及疗效的对比研究[J].中华耳科学杂志,2009,7(2):176-177.
[22] 何磊,周慧芳,杨彩虹,等.激素治疗合并2型糖尿病不同血糖水平突发性聋患者的疗效分析[J].医学信息,2014, 28(5):28-29.
[23] 严孝花,韩璐荣.甲泼尼龙治疗2型糖尿病并发突发性聋患者疗效研究[J].临床军医杂志,2017,45(9):988-989
[24] 王明明,樊兆民,侯志强,等.糖皮质激素局部注射与全身应用在特发性突发性聋分型治疗中的疗效[J].中华耳鼻咽喉头颈外科杂志,2014,49(1):11-15. |
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