糖尿病对中老年男性下尿路症状的影响

doi:10.20047/j.issn1673-7210.2023.21.16

Abstract
Figure/Table
References (26)
Related Citation (15)

Download: PDF (580 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the influence of diabetes mellitus on lower urinary tract symptoms in middle-aged and elderly men. Methods A total of 252 middle-aged and elderly male patients admitted to the First Affiliated Hospital of Xinxiang Medical University for lower urinary tract symptoms from December 2021 to March 2022 were selected as the study objects, and were divided into diabetes mellitus group (83 cases) and non-diabetes mellitus group (169 cases) according to whether they had diabetes mellitus. The international prostate symptom score (IPSS), health-related quality of life (HRQL) questionnaire, free urine flow rate examination, and residual urine volume (RUV) measurement were performed between the two groups. The differences of each scale score between the two groups were compared, and the differences of each scale score between the different disease course (≥ five years, 55 cases; ＜ five years, 28 cases) and fasting plasma glucose (FPG) (＞10.0 mmol/L, 38 cases; ≤10.0 mmol/L, 45 cases) in diabetes mellitus group were compared. Results The maximum urine flow rate and average urine flow rate in the diabetes mellitus group were lower than those in the non-diabetes mellitus group, and the scores of IPSS, HRQL questionnaire, and urinary storage period were higher than those in the non-diabetes mellitus group, the differences were statistically significant (P＜0.05). The urine storage period score and HRQL questionnaire score of diabetic patients with disease course≥ five years were lower than those of patients with disease course ＜ five years, and the differences were statistically significant (P＜0.05). The average urine flow rate of diabetic patients with FPG＞10.0 mmol/L was higher than that of patients with FPG≤10.0 mmol/L, and the difference was statistically significant (P＜0.05). Conclusion In middle-aged and elderly men with diabetes, lower urinary tract symptoms are more severe, and their quality of life is also reduced.

Key words： Diabetes mellitus Lower urinary tract symptoms Middle-aged and elderly men Urinary flow rate International prostate symptom score

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHANG Songwei1 WANG Fucheng1 ZHANG Huiqing1 WEN Jianguo2

Cite this article:

ZHANG Songwei1 WANG Fucheng1 ZHANG Huiqing1 WEN Jianguo2. Influence of diabetes mellitus on lower urinary tract symptoms in middle-aged and elderly men[J]. 中国医药导报, 2023, 20(21): 76-79.

URL:

https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.21.16 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I21/76

[1] 张杜丹，唐迅，靳丹瑶，等.中国成年人糖尿病患病率Meta分析[J].中华流行病学杂志，2018，39（6）：852-857.
[2] 陈蓉琼，方克伟.糖尿病膀胱的发病机制及临床诊疗进展[J].临床荟萃，2018，33（7）：641-644.
[3] Wittig L，Carlson KV，Andrews JM，et al. Diabetic bladder dysfunction：A review [J]. Urology，2019，123：1-6.
[4] Bolgeo T，Maconi A，Bertolotti M，et al. Physiopathology of the diabetic bladder [J]. Arch Ital Urol Androl，2020，92（4）：10.
[5] 李彦锋.男性下尿路症状诊断和治疗中国专家共识[J].中华男科学杂志，2021，27（12）：1129-1139.
[6] 刘泽民，刘百成，王旺龙，等.门诊良性前列腺增生患者下尿路症状调查及特点分析[J].临床医药实践，2018，27（2）：85-87.
[7] 胡龙芳，王薇，任奇.中老年男性下尿路症状调查及危险因素分析[J].护理学杂志，2018，33（4）：27-30.
[8] 曹会峰，桂士良.尿流率测定及国际前列腺症状评分在前列腺增生患者中的应用[J].中国老年学杂志，2010，30（16）：2377-2378.
[9] 邓小林，张虎，史本涛，等.家庭尿流率测定在下尿路症状患者评估中的研究进展[J].北京大学学报（医学版），2012，44（4）：655-658.
[10] 任衢军，成泽民，杜义堂，等.最大自由尿流率联合残余尿对膀胱出口梗阻致排尿障碍的评估作用[J].医学综述，2015，21（24）：4590-4592.
[11] 徐凌，冯建伟，郎金田，等.尿流动力学参数及血清CRP、PSA水平对老年BPH合并AUR病人的诊断及疗效评估价值[J].实用老年医学，2022，36（4）：395-396，404.
[12] 邱耀均，戴丽，龚泽辉.膀胱扫描仪在测定神经源性膀胱患者残余尿中的应用效果[J].中国社区医师，2020， 36（28）：146-147.
[13] 杜彦斌，吕媛，洪秀琴，等.中国人群糖尿病患病影响因素meta分析[J].中国公共卫生，2020，36（9）：1378-1383.
[14] 顾佳敏，朱聪，訾豪，等.1990—2019年中国良性前列腺增生疾病负担分析[J].解放军医学杂志，2021，46（10）：984-988.
[15] Egan KB. The epidemiology of benign prostatic hyperplasia associated with lower urinary tract symptoms：prevalence and incident rates [J]. Urol Clin North Am，2016，43（3）：289- 297.
[16] 李文华，李健，魏云鸿，等.老年男性下尿路症状与2型糖尿病的相关性[J].昆明医科大学学报，2017，38（3）：127-130.
[17] 方建雄，刘久敏.糖尿病性膀胱病的发病机制及治疗进展[J].国际泌尿系统杂志，2020，40（3）：574-577.
[18] 郭文敏，孙李斌，王东文.糖尿病膀胱研究进展[J].中国全科医学，2020，23（17）：2095-2101.
[19] 王明伟.糖尿病并发症的发病机制及其药物治疗研究进展[J].继续医学教育，2022，36（4）：157-160.
[20] Galì A，Mucciardi G，Butticè S，et al. Correlation Between Advanced Glycation End-Products，Lower Urinary Tract Symptoms and Bladder Dysfunctions in Patients with type 2 Diabetes Mellitus [J]. Low Urin Tract Symptoms，2017，9（1）： 15-20.
[21] 马聪，肖楠.糖尿病膀胱功能障碍发病机制研究进展[J].中国医药，2022，17（10）：1570-1574.
[22] 李娟，陈平，张卫兵.糖尿病与前列腺增生的相关性分析[J].武汉大学学报（医学版），2021，42（2）：338-344.
[23] 王姊娟，杜依青，张建，等.代谢综合征及其诊断指标与重度良性前列腺增生症的相关性研究[J].协和医学杂志，2020，11（6）：703-709.
[24] 商书霞，卫峻枫，赵军魁，等.2型糖尿病患者颈围与良性前列腺增生的相关性研究[J].中国医药导报，2020， 17（6）：77-80.
[25] Papaefstathiou E，Moysidis K，Sarafis P，et al. The impact of Diabetes Mellitus on Lower urinary tract symptoms （LUTS） in both male and female patients [J]. Diabetes Metab Syndr，2019，13（1）：454-457.
[26] 胡一鸣，任颖，邵琦，等.住院患者入院空腹血糖水平与病情转归的关系研究[J].上海交通大学学报（医学版），2011，31（6）：832-835.