保乳手术治疗早期三阴乳腺癌患者的效果及安全性

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Abstract Objective To investigatethe clinical efficacy and security of breast conserving surgery in the treatment of early triple negative breast cancer (TNBC) patients. Methods A total of 110 early TNBC patients admitted to Bozhou People’s Hospital, Anhui Province from January 2018 to February 2021 were selected as study objects. According to the random number table method, they were divided into control group and observation group, with 55 cases in each group. The control group was treated with modified radical mastectomy, and observation group was treated with breast conserving surgery. The amount of intraoperative blood loss, operation time, postoperative drainage time, and the incidence of postoperative complications were compared between two groups, local recurrence and distant metastasis were observed during postoperative follow-up for three months, and the quality of life scores before and after operation were compared. Results The amount of intraoperative blood loss of observation group was lower than that of control group, and operation time and postoperative drainage time were shorter than those of control group, and the differences were statistically significant (P < 0.05). The total incidence of complications in observation group was lower than that in control group, and the difference was statistically significant (P < 0.05). There were no significant differences in local recurrence rate and distant metastasis rate between two groups (P > 0.05). Before operation, there were no significant differences in quality of life scores between two groups (P > 0.05); after operation, the quality of life scores of two groups were higher than those before operation, and observation group was higher than control group, and the differences were statistically significant (P < 0.05). Conclusion Breast conserving surgery for early TNBC patients has significant effect, rapid recovery and high safety, which is worthy of clinical application.

Key words： Breast conserving surgery Triple negative breast cancer Clinical effect Long term effect Security

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	WANG Xiaodong CHEN Dapeng PENG Yongqiang

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WANG Xiaodong CHEN Dapeng PENG Yongqiang. Efficacy and security of breast conserving surgery in the treatment of early triple negative breast cancer patients#br#[J]. 中国医药导报, 2022, 19(8): 109-112.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I8/109

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