结肠息肉术后复发的影响因素分析

Abstract
Figure/Table
References (27)
Related Citation (15)

Download: PDF (623 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To retrospectively analyze the influencing factors of postoperative recurrence of colonic polyps after treatment. Methods A total of 416 patients with colonic polyps hospitalized and received endoscopic treatment in Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from May 2014 to May 2019 were selected. The patients were divided into the recurrence group (216 cases) and the non-recurrence group (200 cases) according to the postoperative recurrence. The clinical data of the patients were retrospectively collected to analyze the influencing factors of postoperative recurrence of colonic polyps. Results The proportion of male, age ≥60 years, non-alcoholic fatty liver disease, hypertension, type 2 diabetes mellitus, operation method of argon-plasma coagulation (APC) and APC combined with high frequency electrical polypectomy, number of polyps ≥3, diameter of polyps ≥10 mm, multiple sites, adenoma, and the levels of body mass index (BMI), uric acid (UA), triglyceride (TG), high density lipoprotein (HDL) in the recurrence group were all higher than those in the non-recurrence group, and the differences were statistically significant (P ＜ 0.05). Multivariate analysis showed that age ≥60 years, non-alcoholic fatty liver disease, hypertension, high BMI, number of polyps ≥3, diameter of polyps ≥10 mm, multiple sites, and adenoma were independent risk factors for colon polyp recurrence (OR ＞ 1, P ＜ 0.05). Conclusion Age ≥60 years, non-alcoholic fatty liver disease, hypertension, number of polyps ≥3, diameter of polyps ≥10 mm, multiple sites, adenoma, high BMI are independent influence factors of recurrence of colonic polyps, may be closely related with the recurrence of colonic polyps, for domestic clinicians guide patients with colonic polyps of follow-up work provide certain reference value.

Key words： Colonic polyps Recurrence Influencing factors

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	GAO Jingjing LU Shiyu DU Shengnan YUAN Yifu JIANG Yuanye▲ CAO Qin▲

Cite this article:

GAO Jingjing LU Shiyu DU Shengnan YUAN Yifu JIANG Yuanye▲ CAO Qin▲. Analysis of the influencing factors of postoperative recurrence of colonic polyps[J]. 中国医药导报, 2022, 19(23): 104-108.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I23/104

[1] Shah J，Shahidullah A. Spontaneous Expulsion per Rectum of a Colorectal Polyp：A Rare and Unusual Case [J]. Gastroenterology Res，2018，1（4）：329-332.
[2] Simon K. Colorectal cancer development and advances in screening [J]. Clin Interv Aging，2016，11：967-976.
[3] Hao Y，Wang Y，Qi M，et al. Risk Factors for Recurrent Colorectal Polyps [J]. Gut Liver，2020，14（4）：399-411.
[4] Harrington LX，Wei JW，Suriawinata AA，et al. Predicting colorectal polyp recurrence using time-to-event analysis of medical records [J]. AMIA Jt Summits Transl Sci Proc，2020，2020：211-220.
[5] 林果为，王吉耀，葛均波.实用内科学[J].15版.北京：人民卫生出版社，2017.
[6] 李益农，陆星华.消化内镜学[J].2版.北京：科学出版社，2004.
[7] Patel SG，Ahnen DJ. Colorectal Cancer in the Young [J]. Curr Gastroenterol Rep，2018，20（4）：15.
[8] Wang QP，He XX，Xu T，et al. Polyp recurrence after colonoscopic polypectomy [J]. Chin Med J，2020，133（17）：2114-2115.
[9] Rutter MD，Bretthauer M，Hassan C，et al. Principles for Evaluation of Surveillance After Removal of Colorectal Polyps：Recommendations From the World Endoscopy Organization [J]. Gastroenterology，2020，158（6）：1529-1533.
[10] Yamaji Y，Mitsushima T，Ikuma H，et al. Right-side shift of colorectal adenomas with aging [J]. Gastrointest Endosc，2006，63（3）：453-458.
[11] Pommergaard HC，Burcharth J，Rosenberg J，et al. Advanced age is a risk factor for proximal adenoma recurrence following colonoscopy and polypectomy [J]. Br J Surg，2016，103（2）：e100-e105.
[12] Hassan C，Quintero E，Dumonceau JM，et al. Post-polypectomy colonoscopy surveillance：European Society of Gastrointestinal Endoscopy （ESGE） Guideline-Update 2020 [J]. Endoscopy，2020，52（8）：687-700.
[13] Levin B，Lieberman DA，McFarland B，et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps，2008：a joint guideline from the American Cancer Society，the US Multi-Society Task Force on Colorectal Cancer，and the American College of Radiology [J]. CA Cancer J Clin，2008，58（3）：130-160.
[14] Laiyemo AO，Doubeni C，Badurdeen DS，et al. Obesity，weight change，and risk of adenoma recurrence：a prospective trial [J]. Endoscopy，2012，44（9）：813-818.
[15] Soltani G，Poursheikhani A，Yassi M，et al. Obesity，diabetes and the risk of colorectal adenoma and cancer [J]. BMC Endocr Disord，2019，19（1）：113.
[16] Saiken A，Gu F. Lifestyle and lifestyle-related comorbidities independently associated with colorectal adenoma recurrence in elderly Chinese people [J]. Clin Interv Aging，2016，11：801-805.
[17] Lin CC，Huang KW，Luo JC，et al. Hypertension is an important predictor of recurrent colorectal adenoma after screening colonoscopy with adenoma polypectomy [J]. J Chin Med Assoc，2014，77（10）：508-512.
[18] Koplay M，Sivri M，Erdogan H，et al. Importance of imaging and recent developments in diagnosis of nonalcoholic fatty liver disease [J]. World J Hepatol，2015，7（5）：769-776.
[19] Cobbina E，Akhlaghi F. Non-alcoholic fatty liver disease（NAFLD）-pathogenesis，classification，and effect on drug metabolizing enzymes and transporters [J]. Drug Metab Rev，2017，49（2）：197-211.
[20] Loomba R，Sanyal AJ. The global NAFLD epidemic [J]. Nat Rev Gastroenterol Hepatol，2013，10（11）：686-690.
[21] Miura K，Ohnishi H. Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease [J]. World J Gastroenterol，2014，20（23）：7381-7391.
[22] Chang ML，Yang Z，Yang SS. Roles of Adipokines in Digestive Diseases：Markers of Inflammation，Metabolic Alteration and Disease Progression [J]. Int J Mol Sci，2020，21（21）：8308.
[23] 张新星，顾清，张璐，等.瘦素和脂联素在老年结直肠腺瘤合并非酒精性脂肪肝患者中的表达及意义[J].世界华人消化杂志，2016，24（10）：1575-1580.
[24] 葛军，华敏，赵冰.内镜下结直肠息肉切除术后复发的危险因素分析[J].中国内镜杂志，2020，26（8）：20-24.
[25] Ate■ ?魻，Sivri B，K?覦l?覦?觭kap S. Evaluation of risk factors for the recurrence of colorectal polyps and colorectal cancer [J]. Turk J Med Sci，2017，47（5）：1370-1376.
[26] Bonnington SN，Rutter MD. Surveillance of colonic polyps：Are we getting it right？[J]. World J Gastroenterol，2016，22（6）：1925-1934.
[27] Abu-Freha N，Katz LH，Kariv R，et al. Post-polypectomy surveillance colonoscopy：Comparison of the updated guidelines [J]. United European Gastroenterol J，2021，9（6）：681-687.