Abstract Objective To analyze the influencing factors of hypertension in hemodialysis patients with end-stage renal disease. Methods A retrospective analysis method was used to collect the clinical data of 100 patients with end-stage renal disease who underwent hemodialysis in the People’s Hospital of Bozhou from January 2020 to January 2021. According to the incidence of hypertension during dialysis, the patients were divided into the occurrence group and the non-occurrence group. The clinical data of the two groups were collected, and the influencing factors of hypertension complicated by end-stage renal disease hemodialysis patients were analyzed. Results Among the 100 patients with end-stage renal disease, a total of 76 cases were complicated with hypertension during hemodialysis, accounting for 76.00%. The proportion of patients using erythropoietin (EPO) in the occurrence group was higher than that in the non-occurrence group, while the levels of serum C-reactive protein (CRP), homocysteine (Hcy), and phosphorus (P) were higher than those in the non occurrence group, and the differences were statistically significant (P ＜ 0.05). Logistic regression analysis showed that, the use of EPO and the excessive production of CRP, Hcy, and P were the risk factors of hypertension in hemodialysis patients with end-stage renal disease (OR ＞ 1, P ＜ 0.05). Conclusion Hemodialysis patients with end-stage renal disease have a higher risk of hypertension, the use of EPO, excessive production of serum CRP, Hcy, and P are the influencing factors of hypertension in hemodialysis patients with end-stage renal disease.
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