Analysis of risk factors related to colorectal polyps
ZHANG Qian1 REN Junyao1 XING Jie1 SUN Xiujing1 YUE Bing2 ZHU Shengtao1 LI Peng1 ZHANG Shutian1
1.Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University National Clinical Research Center for Digestive Disease Beijing Digestive Disease Center Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing 100050, China;
2.Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Abstract Objective To explore the risk factors of colorectal polyps found in colonoscopy. Methods A retrospective analysis of 662 patients who underwent colonoscopy at the Digestive Endoscopy Center of Beijing Friendship Hospital, Capital Medical University from March 2013 to November 2014. According to the results of endoscopic and pathological diagnosis, a total of 255 patients with colorectal polyps were included in the polyp group, and 407 subjects with normal results or inflammatory lesions were included in the control group. The age, gender, personal history, past history and other factors of patients were collected, and the related risk factors that affect the occurrence of colorectal polyps were analyzed. Results Age, body mass index (BMI), proportion of males, proportion of light physical labor, smoking rate, alcohol consumption, prevalence of hypertension and previous prevalence of polyps of the polyp group were higher than those of the control group, and the differences were statistically significant (P ＜ 0.05). Multivariate logistic regression model analysis showed that age (OR = 1.050), BMI (OR = 1.059), smoking (OR = 2.359), alcohol (OR = 1.644) and history of previous polyps (OR = 1.758) were independent risk factors for colorectal polyps (P ＜ 0.05); age (OR = 1.049), male (OR = 0.381), smoking (OR = 1.784), and history of polyps (OR = 2.301) were independent risk factors for multiple colorectal polyps (P ＜ 0.05). Conclusion Age, gender, BMI, smoking, drinking, and history of polyps may be independent risk factors for the occurrence or occurrence of colorectal polyps. Therefore, when performing colonoscopy, attention should be paid to comprehensively considering the relevant risk factors of patients, and focusing on screening and follow-up of high-risk groups to improve the detection rate of adenomas.
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