Analysis on medication rule of Professor Mao Dexi in treating chest arthralgia and heartache based on data mining technology
ZHAO Chuang1 LU Yongping2 SHI Ruoyu1
1.The Second Clinical Medical College, He’nan University of Chinese Medicine, He’nan Province, Zhengzhou 450000, China;
2.Department of Functional Examination, He’nan Hospital of Traditional Chinese Medicine, He’nan Province, Zhengzhou 450000, China
Abstract Objective To analyze the medication rule of Professor Mao Dexi in the treatment of chest arthralgia and heartache based on data mining technology. Methods The outpatient medical records of Professor Mao Dexi in treating chest arthralgia and heartache in the Famous Medical Hall of He’nan Hospital of Traditional Chinese Medicine from February 2018 to January 2020 were collected and collated. Professor Mao Dexi’s prescription for chest arthralgia and heartache was analyzed by using traditional Chinese medicine inheritance assistant system (V2.5) through data mining method, such as frequency analysis, association rules, complex entropy clustering analysis, and so on. Results There were 128 prescriptions for chest arthralgia and heartache, involving 145 traditional Chinese medicine, of which, cold and warm were the main ones, and pungent, bitter and sweet medicines accounted for a large proportion. The lung, spleen, stomach, heart and liver meridians appeared more frequently. The top five drugs used frequently were Salviae Miltiorrhizae Radix et Rhizoma, Paeoniae Radix Rubra, Chuanxiong Rhizoma, Dalbergiae Odoriferae Lignum, Allii Macrostemonis Bulbus. The most frequently used drug combinations were Paeoniae Radix Rubra-Salviae Miltiorrhizae Radix et Rhizoma, Chuanxiong Rhizoma-Salviae Miltiorrhizae Radix et Rhizoma, Dalbergiae Odoriferae Lignum-Salviae Miltiorrhizae Radix et Rhizoma, Dalbergiae Odoriferae Lignum-Paeoniae Radix Rubra, Dalbergiae Odoriferae Lignum-Paeoniae Radix Rubra-Salviae Miltiorrhizae Radix et Rhizoma. Eight core drug combinations and four potential new prescriptions were found. Conclusion Professor Mao Dexi is good at promoting blood circulation and removing blood stasis, regulating qi and resolving phlegm, tonifying qi and nourishing yin, consolidating the root, combining cold and heat, reinforcing and reducing, and treating both symptoms and root causes.
ZHAO Chuang1 LU Yongping2 SHI Ruoyu1. Analysis on medication rule of Professor Mao Dexi in treating chest arthralgia and heartache based on data mining technology[J]. 中国医药导报, 2021, 18(14): 132-135,144.
