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Effects of circRNAs on maternal reproductive organs and embryo development during pregnancy |
JIANG Yuanxin WANG Yu |
School of Basic Medicine, Inner Mongolia Medical University, the Inner Monggol Autonomous Region, Hohhot 010000, China
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Abstract circularRNA (circRNAs) play an important regulatory role in pregnancy, this regulation is mainly manifested in the regulation of ovarian and uterus and other reproductive organs, and embryonic development process. At present, there are many studies on the important regulatory role of circRNAs in cancer, embryogenesis and differentiation during pregnancy have similar molecular mechanisms with cancer. However, there are few studies on the regulatory role of circRNAs during pregnancy. This paper reviewed the latest literature on the regulatory role of circRNAs in pregnancy, to investigate how circRNAs regulates oocyte development, embryo implantation, and embryo development. Exploring the application of circRNAs in pregnancy is helpful to search for new molecular markers of disease, and also broaden the thinking of infertility diagnosis and treatment.
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