肾透明细胞癌胆囊转移1例报告并文献复习

doi:10.20047/j.issn1673-7210.2022.33.40

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Abstract Clear cell renal cell carcinoma (ccRCC) is the most common pathological type of renal cell carcinoma (RCC), accounting for about 3%-5% of adult malignant tumors. RCC is mainly with vascular metastasis, which is common in organs or tissues such as lung, liver, bone, adrenal gland, and brain, but it is very rare that RCC metastasis to gallbladder. This report retrospectively analyzed the case data of a patient with gallbladder metastasis found eight years after radical resection of left ccRCC in the Department of Hepatobiliary Surgery of Guangzhou Red Cross Hospital Jinan University in January 2021. The patient was found to have gallbladder space occupying lesions and right lung nodules (no cancer cells were found in the nodule by out-of-hospital biopsy before) after admission. The lesion was pathologically confirmed as ccRCC gallbladder metastasis during subsequent laparoscopic radical gallbladder cancer surgery. However, after two months’ follow-up, a new nodule was found in the left lung, and was pathologically confirmed to be metastatic ccRCC, which was intervened by delivering Sunitinib. After 15 months’ follow-up, there was no recurrence of primary or other tumors, except for the progression of lung metastases. Preoperative diagnosis of ccRCC gallbladder metastasis based on clinical symptoms, signs and imaging data is challenging, which should be further proved by pathological examination. Therefore, the current report aimed to help better understanding the disease via reviewing the corresponding literature including imaging, pathological features, diagnosis, treatment, and prognosis.

Key words： Gallbladder neoplasms Neoplasm metastasis Clear cell renal cell carcinoma Diagnosis and differential diagnosis Cholecystectomy

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	ZHU Shanfei YUAN Wei DU Yongliang WU Fan YAN Yong WANG Bailin

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ZHU Shanfei YUAN Wei DU Yongliang WU Fan YAN Yong WANG Bailin. A case report and literature review of gallbladder metastasis of clear cell renal cell carcinoma[J]. 中国医药导报, 2022, 19(33): 176-179,192.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.33.40 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I33/176

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