Effects of cognitive behavioral therapy on sleep quality in patients with cancer on chemotherapy
WANG Aihong1 ZHOU Xiaoyan2 WANG Mingquan3
1.Medical Experimental Center, Medical College of Yan′an University, Shaanxi Province, Yan′an 716000, China;
2.Key Laboratory of Cancer Prevention and Ttreatment of Yan′an City, Shaanxi Province, Yan′an 716000, China;
3.Fepartment of Interventional Radiology, Affiliated Hospital of Yan′an University, Shaanxi Province, Yan′an 716000, China
Abstract：Objective To determine effects of cognitive behavioral therapy on sleep quality in cancer patients treated with chemotherapy. Methods From January 2010 to January 2015, in Affiliated Hospital of Yan′an University, 88 cancer patients received chemotherapy were selected, they were divided into observation group (43 cases) and control group (45 cases). The control group was given routine treatment, the observation group was given cognitive behavioral therapy based on the control group. The Pittsburgh Sleep Quality Index (PSQI) and Zung′s self-rating anxiety scale (SAS), Zung′s self-rating depression scale (SDS) were used to assess the sleep quality and psychological status after intervention 1 month and 3 months. Results After 3 months intervention, SAS scores ,SDS scores and PSQI of two groups were significantly lower than before the intervention, the differences were statistically significant (P < 0.05); SAS scores, SDS scores and PSQI of the observation group were lower than control group, the differences were statistically significant (P < 0.05). Conclusion Cognitive behavioral therapy significantly reduces the levels of depression, anxiety and the severity of insomnia in cancer patients treated with chemotherapy.
王爱红1，2 周小燕1，2 王明全3▲. 认知行为疗法对癌症患者化疗期间睡眠质量的干预效果[J]. 中国医药导报, 2018, 15(11): 154-157.
WANG Aihong1 ZHOU Xiaoyan2 WANG Mingquan3 . Effects of cognitive behavioral therapy on sleep quality in patients with cancer on chemotherapy. 中国医药导报, 2018, 15(11): 154-157.
[1] Otte JL，Carpenter JS，Russell KM，et al. Prevalence，severity，and correlates of sleep-wake disturbances in long-term breast cancer survivors [J]. J Pain Symptom Manage，2010， 39（3）：535-547.
[2] Ebede CC，Jang Y，Escalante CP. Cancer-related fatigue in cancer survivorship [J]. Med Clin North Am，2017，101（6）：1085-1097.
[3] 卢海霞，李霞，韩樱.认知行为疗法对中国失眠患者睡眠质量影响的Meta分析[J].中国老年学杂志，2017，37（3）：685-688.
[4] Savard J，Ivers H，Savard MH，et al.Long-term effects of two formats of cognitive behavioral therapy?for insomnia comorbid with breast cancer [J]. Sleep，2016，39（4）：813-823.
[5] Aricò D，Raggi A，Ferri R.Cognitive behavioral therapy for insomnia in breast cancer survivors： a review of the literature [J]. Front Psychol，2016，7：1162.
[6] Zung WW. A rating instrument for anxiety disorders [J]. Psychosomatics，1971，12（6）：371-379
[7] Zung WW. A self-rating depression scale [J]. Arch Gen Psychiatry，1965，12： 63-70.
[8] Buysse，DJ，Reynolds CF 3rd，Monk TH，et al. The Pittsburgh sleep quality index： A new instrument for psychiatric practice and research [J]. Psychiatry Res，1989，28（2）：193-213.
[9] Yi JC，Syrjala KL. Anxiety and depression in cancer survivors [J]. Med Clin North Am，2017，101（6）：1099-1113.
[10] Rodrigues AR，Trufelli DC，Fonseca F，et al. Fatigue in patients with advanced terminal cancer correlates with inflammation，poor quality of life and sleep，and anxiety/depression [J]. Am J Hosp Palliat Care，2016，33（10）：942-947.
[11] Yennurajalingam S，Tayjasanant S，Balachandran D，et al. Association between daytime activity，fatigue，sleep，anxiety，depression，and symptom burden in advanced cancer patients：a preliminary report [J]. J Palliat Med，2016，19（8）：849-56.
[12] Palesh OG，Roscoe JA，Mustian KM，et al. Prevalence，demographics，and psychological associations of sleep disruption in patients with cancer： University of roches?鄄ter cancer center-community clinical oncology program [J]. J Clin Oncol，2010，28（2）：292-298.
[13] Hong JS，Tian J and Wu LH. The influence of chemotherapy-induced neurotoxicity on psychological distress and sleep disturbance in cancer patients [J]. Cur Oncol，2014，21（4）：174-180.
[14] 陈学芬，王继伟，宫霄欢，等.心理社会干预对癌症生存者生命质量改善的研究进展[J].中华预防医学杂志，2015， 49（2）：189-202.
[15] Kazantzis N，Brownfield NR，Mosely L，et al. Homework in cognitive behavioral therapy： a systematic review of adherence assessment in anxiety and depression （2011-2016）[J]. Psychiatr Clin North Am，2017，40（4）：625-639.
[16] Powers MB，de Kleine RA，Smits JAJ. Core mechanisms of cognitive behavioral therapy for anxiety and depression：a review [J]. Psychiatr Clin North Am. 2017，40（4）：611-623.
[17] Matthews H，Grunfeld EA，Turner A. The efficacy of interventions to improve psychosocial outcomes following surgical treatment for breast cancer：a systematic review and meta-analysis [J]. Psychooncology，2017，26（5）：593-607.
[18] Peoples AR，Garland SN，Perlis ML，et al. Effects of cognitive behavioral therapy for insomnia and armodafinil on quality of life in cancer survivors：a randomized placebo-controlled trial [J]. J Cancer Surviv，2017，11（3）：401-409.
[19] Heckler CE，Garland SN，Peoples AR，et al. Cognitive behavioral therapy for insomnia，but not armodafinil，improves fatigue in cancersurvivors with insomnia： a randomized placebo-controlled trial [J]. Support Care Cancer.，2016，24（5）：2059-2066.
[20] Roscoe JA，Garland SN，Hecker CE，et al. Randomized placebo-controlled trial of cognitive behavioral therapy and armodafinil for insomnia after cancer treatment [J]. J Clin Oncol，2015，33（2）：165-171.
[21] Kamen C，Garland SN，Heckler CE，et al. Social support，insomnia，and adherence to cognitive behavioral therapy for insomnia after cancer treatment [J]. Behav Sleep Med，2017，27：1-13.
[22] Zhou ES，Partridge AH，Recklitis CJ. A pilot trial of brief group cognitive-behavioral treatment for insomnia in an adult cancer survivorship program [J]. Psychooncology，2017，26（6）：843-848.
[23] Cape J，Leibowitz J，Whittington C，et al. Group cognitive behavioural treatment for insomnia in primary care： a randomized controlled trial [J]. Psychol Med，2016，46（5）：1015-1025.
[24] Seyffert M，Lagisetty P，Landpraf J，et al. Internet-delivered cognitive behavioral therapy to treat insomnia：a systematic review and meta-analysis [J]. PLoS One，2016， 11 （2）：e0149139.
[25] Savard J，Savard MH，Ivers H. Moderators of treatment effects of a video-based cognitive behavioral therapy for insomnia comorbid with cancer[J]. Behav Sleep Med，2016，5：1-19.
[26] Susanna BH，Jacques JDM，Hester SA，et al. Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer：design of a multicenter，randomized controlled trial [J]. BMC Cancer，2015，15：321.
2018, Vol. 15 
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