Clinical effect of Yougui Pills combined with ginger moxibustion in the treatment of knee osteoarthritis with syndrome of yang deficiency and coagulated cold
SHAO Jieqi ZENG Zhijiang YANG Min LU Xiangran ZHONG Qiusheng
Internal Medicine Department of Traditional Chinese Medicine, the Third People's Hospital of Dongguan City, Guangdong Province, Dongguan 523326, China
Abstract:Objective To explore the clinical curative effect of Yougui Pills combined with ginger moxibustion in the treatment of knee osteoarthritis with syndrome of yang deficiency and coagulated cold. Methods One hundred and ten cases of knee osteoarthritis patients with syndrome of yang deficiency and coagulated cold treated in the Third People's Hospital of Dongguan City form June 2013 to June 2017 were selected and randomly divided into control group and experimental group by random number table method, with 55 cases in each group. The control group was given oral Yougui Pills, the experimental group was given Yougui Pills combined with ginger moxibustion. The serum inflammatory activity indicators, serum immunological indices, and the scores of Lequesne index and yang deficiency syndrome of the two groups before and after treatment were compared. Results After treatment, the serum inflammatory activity indicators of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and 28 human body joint function assessment (DAS28), the serum immunological indices of interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and the scores of Lequesne index and yang deficiency syndrome in the two groups were significantly lower than those before treatment (P < 0.05), and the serum inflammatory activity indicators, serum immunological indices, the scores of Lequesne index and yang deficiency syndrome in the experimental group after treatment were all significantly lower than those of control group at the same period, the differences were all statistically significant (P < 0.05). Conclusion Yougui Pills combined with ginger moxibustion in the treatment of knee osteoarthritis with syndrome of yang deficiency and coagulated cold has remarkable curative effects, which can significantly improve the inflammatory symptoms and immunity, relieve pain, with high safety.
邵洁琦 曾志江 杨敏 陆向然 钟秋生. 右归丸联合隔姜灸治疗阳虚寒凝型膝骨性关节炎的临床效果[J]. 中国医药导报, 2018, 15(10): 106-109.
SHAO Jieqi ZENG Zhijiang YANG Min LU Xiangran ZHONG Qiusheng. Clinical effect of Yougui Pills combined with ginger moxibustion in the treatment of knee osteoarthritis with syndrome of yang deficiency and coagulated cold. 中国医药导报, 2018, 15(10): 106-109.