1.Department of General Surgery, the Second People′s Hospital of Kashgar, Xinjiang Uygur Autonomous Region, Kashgar 844000, China;
2.Department of Hospital-Acquired Infection Control, the Second People′s Hospital of Kashgar, Xinjiang Uygur Autonomous Region, Kashgar 844000, China;
3.Department of Medical, the Second People′s Hospital of Kashgar, Xinjiang Uygur Autonomous Region, Kashgar 844000, China
Abstract：Objective To investigate the characteristics of lipid metabolism and stone composition in the patients with simple cholecystolithiasis of Uyghur people in Kashgar region. Methods One hundred and eighty-eight patients with simple cholecystolithiasis treated in the Second People′s Hospital of Kashgar from January 2015 to December 2016 were selected as the patient group, and 172 healthy examined people were selected as the normal control group. The blood lipid levels and stone composition of each group were checked. The differences on plasma lipid levels and gallstone compositions in different gender of the patient group were analyzed. Results The contents of plasma CHOL, TG and APO-B in the patient group were significantly higher than those in the normal control group (P < 0.05). The contents of plasma HDL-C and APO-A1 levels were lower in the female patients than in the men patients (P < 0.05) in the patients group, while cholelithiasis was mainly composed of cholesterol stone (56.13%). Conclusion Abnormal lipid metabolism is one of the causes of cholecystolithiasis, especially in female.
阿力木江·阿布都热衣木1▲ 木沙江·阿布都克力木1 斯皮热古丽·阿布都卡地2▲ 奴尔艾力·卡的3. 喀什地区维吾尔族胆囊结石患者结石成分和脂代谢特点分析[J]. 中国医药导报, 2018, 15(10): 68-71.
Alimujiang·ABUDUREYIMU1▲ Mushajiang·ABUDUKELIMU1 Sipireguli·ABUDUKADI2▲ Nueraili·KADI3. Analysis of the characteristics of lipid metabolism and stone composition in patients with cholecystolithiasis of Uyghur people in Kashgar region. 中国医药导报, 2018, 15(10): 68-71.
[1] Wei S. The clinical application of the hard gallbladder endoscope combined with soft choledochoscope in the surgery of laparoscopic microscopic trauma for the removal of calculi and preservation of gallbladder [J]. J Laparoendosc Adv Surg Tech A（Part A），2013，23（2）：106-108.
[2] 陈智勇，李钢.胆囊壁间结石与胆囊腔内结石的临床特点比较[J].现代消化及介入诊疗，2015，20（4）：392-394.
[3] 陆世锋，俞渊.83例广西壮族居民胆囊结石与血脂水平关系的研究[J].广西中医学院学报，2012，15（2）：11-12.
[4] 孔亮.胆囊壁间结石与胆囊结石的成分比较[J].临床合理用药，2016，9（7A）：37-38.
[5] 陈子广.血糖、血脂水平与胆囊结石发病的关系分析[J].医学理论与实践，2015，28（7）：910-911.
[6] 吴大卫.胆囊结石成因及其相关关系研究综述[J].医学信息，2011（8）：4124-4125.
[7] Kruger PC，Geraghty CM，Parsons PJ. Development of caprine liver quality control materials for trace element analysis of biological tissues. Accreditation and Quality Assurance，2010，15（8）：451-458.
[8] 郝文立，王帅.胆囊结石与高脂血症及中医体质的相关性研究[J].重庆医学，2016，45（19）：2632-2634.
[9] 苗彦国，薛东波，张伟辉.胆囊胆固醇结石成因及其治疗研究进展[J]. 肝胆胰外科杂志，2016，28（2）：155-157.
[10] Wu T，Chang MJ，Xu YJ，et al. Protective effect of Calculus bovis sativus on intrahepatic cholestasis in rats induced by -Naph-t hylisothiocyanate [J]. Am J Chin Med，2013，41（6）：1393-1405.
[11] 邬志韧，刘刚，瞿新刚，等.人体胆囊结石难溶物的组成及在其胆石形成过程中的作用[J].中国医学物理学杂志，2008，25（1）：503-505.
[12] 沈安红.胆囊结石患者血脂水平检测分析[J].国际检验医学杂志2012，33（20）： 2552-2554.
[13] 林晶，陈进宏.胆汁代谢相关调节蛋白与胆囊胆固醇结石[J].外科理论与实践，2013，18（5）：493-496.
[14] 郝文立，王帅.胆囊结石与高脂血症及中医体质的相关性研究[J].重庆医学，2016，45（19）：2632-2634.
[15] 廖雪梅，王雪华，熊志勇，等.胆囊结石饮食相关影响因素的横断面调查[J].中华肝脏外科手术学电子杂志，2016，5（6）：398-403.
[16] 周辉芳，张晓玲，史美缓.胆囊结石病因与致石疾病研究进展[J].河北医科大学学报，2010，31（8）：1029-1032.
[17] 徐丛荣，魏建威，曾敏，等.胆囊结石与血脂水平的相关性研究[J].国际检验医学杂志，2013，34（5）：623-624.
[18] 张小军，曹广文，朱建未.浦东新区南汇区域胆囊结石与血糖、血脂、脂肪肝相关因素分析[J].重庆医学，2017，46（7）：955-957.
[19] 吕永峰，孙海明，王晓年，等.胆囊壁胆固醇结晶与胆囊炎或胆囊结石相关性的初步观察[J].肝胆胰外科杂志，2013，25（3）：232-233.
[20] 张静，刘静，陈丹，等.新疆地区体检人群胆囊结石与代谢综合征及其组分相关性分析[J].中华实用诊断与治疗杂志2016，30（9）：894-897.
2018, Vol. 15 
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