Application value of intracranial pressure monitoring in patients with acute severe craniocerebral injury
DING Jian1 SHENG Luoping2
1.Department of Neurosurgery, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai 201700, China;
2.Department of Neurosurgery, Zhujiajue People's Hospital, Shanghai 201700, China
Abstract:Objective To explore the application value of intracranial pressure monitoring(IPM) in patients with acute severe craniocerebral injury (ASCI). Methods From June 2015 to October 2016, 96 patients with ASCI admitted to Department of Neurosurgery of Qingpu Branch Hospital of Zhongshan Hospital Affiliated to Fudan University were selected, and divided into study group and control group by random number table, with 48cases in each group. The control group was given routine clinical treatment, the study group was given IPM on the basis of routine treatment in the control group, and targeted treatment according to the patient's monitoring results. Follow-up was conducted for 6 months, the conditions of prognosis, use time of mannitol, dosage of mannitol and hospital stay, postoperative complications between two groups were compared. Results The conditions of prognosis in the study group was better than control group, the difference was statistically significant (P < 0.05). The use time of mannitol and hospital stay in the study group were shorter than those of control group (P < 0.05), the dosage of mannitol was lower than control group (P < 0.05). The upper digestive tract hemorrhage, electrolyte disorders and renal damage rate in the study group were lower than those of control group, the difference were statistically significant (P < 0.05). Conclusion IPM should be effective in the treatment of patients with ASCI, which can effectively reduce the use time and dosage of mannitol, shorten the length of hospital stay and reduce the incidence of postoperative complications. The safety is better, and it is worthy of clinical application.
[1] Bashir SA, Rasool A, Zaroo MI,et al. Bear maul craniocerebral trauma in Kashmir Valley [J]. J Craniofac Surg,2013, 24(1):2-5.
[2] Jang SH,Kwon HG. Aggravation of an injured dentato-rubro-thalamic tract in a patient with mild traumatic brain injury:a case report [J]. Medicine(Baltimore),2017,96(43):e8 253.
[3] 史忠岚,卢培刚,袁绍纪,等.持续有创颅内压监测对重型颅脑损伤病人救治的临床意义[J].中国微侵袭神经外科杂志,2015,20(4):161-163.
[4] 甘宁,刘思思,李英姿,等.重型颅脑损伤患者改良大骨瓣减压术中渐进减压与常规减压对比观察[J].山东医药,2017,57(27):70-72.
[5] 杨艳萍.格拉斯哥昏迷评分在颅脑损伤观察中的应用[J].实用医技杂志,2007,14(10):1326-1327.
[6] 于洋,张琳瑛,朱志中,等.电刺激治疗重型颅脑损伤昏迷患者的疗效观察[J].中华物理医学与康复杂志,2014, 36(3):214-216.
[7] Edlow BL,Chatelle C,Spencer CA,et al. Early detection of consciousness in patients with acute severe traumatic brain injury [J]. Brain,2017,140(9):2399-2414.
[8] Jones A,Jarvis P. Review of the potential use of blood neuro-biomarkers in the diagnosis of mild traumatic brain injury [J]. Clin Exp Emerg Med,2017,4(3):121-127.
[9] 谯飞,范润金,张逵,等.颅内压监测在闭合性重型颅脑损伤患者中的应用[J].西部医学,2015,27(6):888-890.
[10] 于海东,高麟,李海龙,等.持续颅内压监测在重型颅脑损伤患者治疗中的应用[J].中国临床研究,2015,28(2):212-213.
[11] 刘芬莲,翁洁清,李晓敏,等.重型颅脑损伤术后患者持续颅内压监测的护理体会[J].解放军护理杂志,2015, 32(3):46-48.
[12] 李奕冉,孙玉明,俞卫锋,等.深镇静在重型颅脑损伤患者治疗中的临床价值研究[J].中华全科医学,2017,15(9):1463-1465.
[13] 陈锦镜,林喜容,周少鹏,等.有创颅内压监测应用于重型颅脑损伤术后的临床意义[J].中国现代药物应用,2015, 9(12):9-10.
[14] Boone DR,Leek JM,Falduto MT,et al. Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury [J]. PLoS One,2017,12(10):185 943-185 944.
[15] 王翊飞,张李涛,周海,等.标准大骨瓣减压术联合依达拉奉对重型颅脑损伤患者血清S100β、IL-6和颅内压的影响[J].中国医院统计,2017,24(3):209-212.
[16] 张广平,申海鸣,高树涛,等.重型颅脑损伤颅内压、脑温、脑电图与预后的相关性研究[J].中华神经外科杂志,2016,31(4):374-375.
[17] 林立超,杨建雄,叶志其,等.重型颅脑损伤持续颅内压及脑灌注压监护的临床研究[J].中国当代医药,2017, 24(9):43-45.
[18] 董伦,汤灿,张恒柱,等.颅内压及脑电双频指数联合监测在重型颅脑外伤患者术后临床应用中的研究[J].国际外科学杂志,2017,44(7):464-467.
[19] Liu H,Anders F,Thanos S,et al. Hydrogen sulfide protects retinal ganglion cells against glaucomatous injury in vitro and in vivo [J]. Invest Ophthalmol Vis Sci,2017,58(12):5129-5141.
[20] 方黎晓,胡少玄,徐洪飞,等.有创颅内压监测在重型颅脑损伤患者术后治疗中的价值[J].检验医学与临床,2016, 13(12):1631-1632.