加味小柴胡颗粒治疗经气不利型后循环缺血性眩晕的临床效果

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摘要目的观察加味小柴胡颗粒治疗经气不利型后循环缺血性眩晕的临床效果。方法选取2019年4月至2020年12月北京中西医结合医院收治的72例经气不利型后循环缺血性眩晕患者作为研究对象，根据随机数字表法将其分为观察组和对照组，每组各36例。两组均予以常规治疗，观察组在此基础上加用加味小柴胡颗粒，总疗程为2周。观察两组临床疗效、中医证候积分、眩晕程度评分和血清超氧化物歧化酶（SOD）水平的差异。结果治疗后，观察组总有效率高于对照组，差异有统计学意义（P ＜ 0.05）。治疗前两组中医证候积分、眩晕程度评分比较，差异无统计学意义（P ＞ 0.05），治疗后两组中医证候积分、眩晕程度评分均较治疗前降低，且观察组低于对照组，差异有统计学意义（P ＜ 0.05）。治疗前，两组SOD比较，差异无统计学意义（P ＞ 0.05），治疗后两组SOD均较治疗前升高，且观察组高于对照组，差异有统计学意义（P ＜ 0.05）。结论加味小柴胡颗粒治疗经气不利型后循环缺血性眩晕效果确切，可以明显改善后循环缺血性眩晕患者的中医证候，缓解眩晕复发，提高血清SOD水平，增强机体的抗氧化能力，保护脑组织。

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	仝小玲1 冯学功1 张连文2

关键词 ：后循环缺血性眩晕, 经气不利证, 加味小柴胡

Abstract：Objective To observe the clinical efficacy of modified Xiaochaihu Granules in the treatment of posterior circulation ischemic vertigo with syndrome of inhibited flow of meridian qi. Methods A total of 72 posterior circulation ischemic vertigo patients with syndrome of inhibited flow of meridian qi admitted to Beijing Hospital of Integrated Traditional Chinese and Western Medicine from April 2019 to December 2020 were selected as the research subjects. According to random number table method, they were divided into observation group and control group, with 36 cases in each group. Both groups were given conventional treatment, on basis of which, observation group was treated with modified Xiaochaihu Granules, the total course of treatment was two weeks. The differences of clinical efficacy, traditional Chinese medicine (TCM) syndrome score, vertigo degree score and serum superoxide dismutase (SOD) of the two groups were observed. Results After treatment, the total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P ＜ 0.05). There was no significant difference of TCM syndrome score and vertigo degree score between the two groups before treatment (P ＞ 0.05). After treatment, the TCM syndrome score and vertigo degree score in the two groups were significantly lower than those before treatment, which in the observation group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). There was no significant difference in SOD level between the two groups before treatment (P ＞ 0.05). After treatment, the SOD levels in the two groups were higher than those before treatment, and the SOD level in the observation group was higher than that in the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Modified Xiaochaihu Granules have a definite curative effect in the treatment of posterior circulation ischemic vertigo with syndrome of inhibited flow of meridian qi, which can obviously improve the TCM symptoms of patients with posterior circulation ischemic vertigo, alleviate the recurrence of vertigo, and raise the serum SOD, enhance the body’s antioxidant capacity and protect brain tissue.

Key words： Posterior circulation ischemic vertigo Syndrome of inhibited flow of meridian qi Modified Xiaochaihu

基金资助:北京中医药薪火传承“3+3”工程冯学功基层老中医传承工作室（2018-JC-11）。

通讯作者: 冯学功（1962-），男，医学博士，主任医师，北京中西医结合医院脑病科主任；研究方向：中西医结合治疗中风偏瘫、眩晕等神经系统疾病。

作者简介: 仝小玲（1980-），女，硕士；研究方向：中西医治疗后循环缺血性眩晕。

引用本文:

仝小玲1 冯学功1 张连文2. 加味小柴胡颗粒治疗经气不利型后循环缺血性眩晕的临床效果[J]. 中国医药导报, 2021, 18(31): 135-138.
TONG Xiaoling1 FENG Xuegong1 ZHANG Lianwen2. Clinical effect of modified Xiaochaihu Granules in the treatment of posterior circulation ischemic vertigo with syndrome of inhibited flow of meridian qi#br#. 中国医药导报, 2021, 18(31): 135-138.

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https://www.yiyaodaobao.com.cn/CN/ 或 https://www.yiyaodaobao.com.cn/CN/Y2021/V18/I31/135

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