Correlation analysis of PM2.5 exposure and physical activity interaction on hypertension in community residents of Suzhou City#br#
JIN Xiaping1 YONG Xuan2 HUA Lan3
1.Preventive Health Care, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Jiangsu Province, Suzhou 215000, China;
2.Medical Affairs Section, Yangjing Community Health Service Center, Pudong New Area, Shanghai 200000, China;
3.the First Department of Disease Prevention, Huishan District Center for Disease Control and Prevention, Jiangsu Province, Wuxi 214000, China
Abstract：Objective To investigate the interaction between of particulate matter 2.5 (PM2.5) exposure and physical activity on hypertension in community residents of Suzhou City. Methods From January 2018 to December 2018, 13 728 study subjects were selected by multi-stage random stratified sampling, and they were divided into four groups according to the PM2.5 quartile cutoff point including low (＜24.32 μg/m3), medium (24.32-＜29.31 μg/m3), high (29.31- ＜31.24 μg/m3), and extremely high (≥31.24 μg/m3), 3432 persons in each group. The blood pressure was measured by an electronic sphygmomanometer (OmronHEM-1300), and the PM2.5 concentration was calculated according to the data published by the “National Urban Air Quality Real-time Release Platform” of the China Environmental Monitoring Station. The metabolic equivalent (MET) was used to calculate the level of physical activity (PA). The logistic regression model was used to analyze the influencing factors of hypertension, and the additive interaction was used for interaction analysis, and the relative excess risk (RERI), the synergy index (SI), interaction attribution percentage (AP) and corresponding 95%CI. Results Compared with the prevalence of patients of different genders, and the difference was statistically significant (P < 0.05). There were statistically significant differences in the age, gender, education level, family history of hypertension, marital status, smoking, and alcohol consumption among people with or without hypertension (P ＜ 0.05). PM2.5, family history of hypertension, smoking, drinking, and physical activity were the influencing factors of hypertension (P ＜ 0.05). After adjusting for factors such as age, gender, family history of hypertension, marital status, smoking, and drinking, etc., PM2.5 exposure and exercise have an additive interaction on the incidence of hypertension, where SI = 2.89, 95%CI: 1.96-3.04; RERI = 0.64, 95%CI: 0.53-0.71; AP=0.31, 95%CI: 0.28-0.42. Conclusion There is an interaction between PM2.5 and PA on the risk of hypertension. PA can reduce the harmful effect of PM2.5 on hypertension.
金霞萍1 雍萱2 华岚3. 苏州市社区居民PM2.5暴露与运动交互作用对高血压的关联分析[J]. 中国医药导报, 2021, 18(30): 64-67.
JIN Xiaping1 YONG Xuan2 HUA Lan3. Correlation analysis of PM2.5 exposure and physical activity interaction on hypertension in community residents of Suzhou City#br#. 中国医药导报, 2021, 18(30): 64-67.
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