Effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity#br#
SUN Yan1 LI Bohui2 WANG Zelin3
1.Department of Cardiology, the Second Affiliated Hospital of Shenyang Medical College, Liaoning Province, Shenyang 110002, China;
2.Department of Outpatient, Shijingshan Retreat for Retired Cadres in Beijing Garrison Area, Beijing 100007, China;
3.Department of Rehabilitation, Beijing Jinkang Traditional Chinese Medicine Hospital, Beijing 102488, China
Abstract：Objective To investigate the clinical effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity and its effect on serum lipoprotein-associated phospholipase A2 (Lp-PLA2) level. Methods A total of 116 patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity admitted to the Department of Cardiology, the Second Affiliated Hospital of Shenyang Medical College from October 2018 to June 2020 were selected as the research objects. They were divided into Western medicine control group and acupuncture treatment group by random number table method, with 58 patients in each group. The Western medicine control group was treated with conventional Western medicine such as coronary artery dilation, anti-platelet aggregation and reducing lipid to stabilize plaque, while the acupuncture treatment group was treated with acupuncture on the basis of the Western medicine control group. Both groups received continuous treatment for 12 weeks. The changes of traditional Chinese medicine syndrome score, Seattle angina questionnaire score, electrocardiogram treadmill exercise test, serum lipid and Lp-PLA2 levels were compared between the two groups. Results The clinical effective rate of traditional Chinese medicine syndrome in acupuncture treatment group was higher than that in Western medicine control group (P ＜ 0.05). After treatment, Seattle angina questionnaire score and electrocardiogram treadmill exercise test index were significantly higher than before treatment (P ＜ 0.05). Traditional Chinese medicine syndrome score and serum levels of triacylglycerol (TAG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and Lp-PLA2 were significantly decreased compared with those before treatment (P ＜ 0.05). Compared with the Western control group, the Seattle angina questionnaire score and electrocardiogram treadmill exercise test index in the acupuncture treatment group after treatment were significantly increased (P ＜ 0.05), and the traditional Chinese medicine syndrome score and levels of serum TAG, TC, LDL-C, and Lp-PLA2 were significantly decreased (P ＜ 0.05). Conclusion The clinical effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity is significant, which can effectively improve the clinical symptoms, improve the quality of life and heart function, and reduce the levels of serum lipid and Lp-PLA2.
孙艳1 李博慧2 王泽林3. 针刺治疗痰浊闭阻证稳定型心绞痛患者的效果[J]. 中国医药导报, 2021, 18(29): 68-72.
SUN Yan1 LI Bohui2 WANG Zelin3. Effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity#br#. 中国医药导报, 2021, 18(29): 68-72.
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