Abstract：Objective To explore the effect of compound insulation on the stress response and coagulation function of abdominal surgery patients. Methods A total of 78 patients undergoing abdominal surgery admitted to Huai’an No.4 People’s Hospital from January to December 2019 were selected and divided into experimental group and control group by random number table method, with 39 cases in each group. The experimental group took compound heat preservation intervention, while the control group took conventional heat preservation intervention. The heat preservation effect, stress response, blood coagulation function and adverse reactions were compared between the two groups. Results There were statistically significant differences in body temperature at different time, groups, and interaction between the two groups (P ＜ 0.05). At 30, 60, 120 minutes, and at the end of the operation, the body temperature of the two groups were lower than before the operation, and the differences were statistically significant (P ＜ 0.05). After anesthesia, 30, 60, 120 minutes, and at the end of the operation, the body temperature of the experimental group were higher than those of the control group, and the differences were statistically significant (P ＜ 0.05). The differences in C-reactive protein (CRP), adrenaline (AD), norepinephrine (NE) content at different time, groups and interactions between the two groups were statistically significant (P ＜ 0.05). At 60 minutes after the operation and at the end of the operation, the levels of CRP, AD, and NE in the two groups were higher than those before anesthesia, and the differences were statistically significant (P ＜ 0.05); at 60 minutes after the operation and at the end of the operation, the contents of CRP, AD, and NE in the experimental group were significantly lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The differences in prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FBG) content at different time, groups and interactions between the two groups were statistically significant (P ＜ 0.05). At 60 minutes after the operation and at the end of the operation, the PT, APTT, and FBG content in the two groups were higher than those before anesthesia, and the differences were statistically significant (P ＜ 0.05); at 60 minutes after the operation and at the end of the operation, the PT, APTT, and FBG content in the experimental group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Compound insulation can help relieve the stress response of patients undergoing abdominal surgery, maintain a relatively stable coagulation function, and reduce the occurrence of adverse reactions such as hypothermia.
张丽娟 王晶晶▲ 闫莉. 复合保温对腹部手术患者应激反应、凝血功能及保温效果的影响[J]. 中国医药导报, 2021, 18(28): 177-180,192.
ZHANG Lijuan WANG Jingjing▲ YAN Li. Impact of compound insulation on the stress response, coagulation function and insulation effect of patients undergoing abdominal surgery. 中国医药导报, 2021, 18(28): 177-180,192.
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