Abstract:Objective To investigate the diagnostic value of ultra-high multiple diffusion sensitivity coefficients (b-value) diffusion weighted imaging-intravoxel incoherent motion (DWI-IVIM) combined with dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) in prostate cancer. Methods The clinical data of 80 patients with suspected prostate cancer admitted to the Second People’s Hospital of Hefei from February 2017 to July 2020 were analyzed. The apparent diffusion coefficient (ADC) and f values of the central region, transitional region, and peripheral region of patients diagnosed by ultra-high b-value DWI-IVIM; volume conversion constant (Ktrans) and rate constant (Kep) values of prostate cancer focal area, hyperplastic area, and normal area were compared; pathological examination results were taken as the gold standard to compare the diagnostic efficacy of different methods. Results ADC values of central region, transitional region, and peripheral region of prostate cancer patients were lower than those of prostate hyperplasia patients, and f values were higher than those of prostate hyperplasia patients, and the differences were statistically significant (P < 0.05). There were significant differences in Ktrans and Kep values between prostate cancer focal area, hyperplasia area, and normal area (P < 0.05). The sensitivity and specificity of ultra-high b-value DWI-IVIM were 91.84% and 77.42% respectively; the sensitivity and specificity of DCE-MRI were 91.84% and 74.19% respectively; the sensitivity and specificity of the combined detection were 95.92% and 90.32% respectively. Conclusion Comparing with ultra-high b-value DWI-IVIM or DCE-MRI single detection, the sensitivity and specificity of combined detection are significantly increased, and has higher diagnostic efficacy for prostate cancer.
王松 夏金翔. 超高b值DWI-IVIM联合DCE-MRI对前列腺癌的诊断价值[J]. 中国医药导报, 2021, 18(28): 156-159.
WANG Song XIA Jinxiang. Study on the diagnostic value of ultra-high b-value DWI-IVIM combined with DCE-MRI in prostate cancer. 中国医药导报, 2021, 18(28): 156-159.