Study of distribution of traditional Chinese medicine syndromes of acquired immunodeficiency syndrome in Lincang, Yunnan based on latent class model
WANG Xing1,2 ZHOU Qing1 LI Qin1 YE Fang3 QU Yuan3 WEN Weibo4
1.School of Basic Medicine, Yunnan University of Chinese Medicine, Yunnan Province, Kunming 650000, China;
2.Department of Emergency, Affiliated Hospital of Yunnan University of Chinese Medicine Zhaotong Hospital of Traditional Chinese Medicine, Yunnan Province, Zhaotong 657000, China;
3.Traditional Chinese Medicine Acquired Immunodeficiency Syndrome Treatment Project Office, Linxiang Hospital of Traditional Chinese Medicine, Yunnan Province, Lincang 677000, China;
4.Department of Endocrinology, the First Affiliated Hospital of Yunnan University of Chinese Medicine Yunnan Provincial Hospital of Traditional Chinese Medicine, Yunnan Province, Kunming 650000, China
Abstract：Objective To explore the regularities of distribution of traditional Chinese medicine syndromes of acquired immunodeficiency syndrome in Lincang area of Yunnan Province. Methods Clinical data of 150 acquired immunodeficiency syndrome patients admitted to Linxiang Hospital of Traditional Chinese Medicine of Yunnan Province from June 2020 to January 2021 were collected to explore the internal correlation between symptoms and syndrome types by latent class model analysis. Results The top 20 main symptoms were greasy fur, white fur, weakness, amnesia, deep pulse, soreness and weakness of waist and knees, dreaminess, reddish tongue, fatigue, lumbago, slippery pulse, bitter taste in mouth, insomnia, arthralgia, alopecia, nocturia, plump tongue, less complexion, heavy body drowsiness, and less menstruation. The latent class 3 had the minimum Bayesian information criterion value (12 496.6106), that was, Model 3 was the best model. According to traditional Chinese medicine symptoms, 150 acquired immunodeficiency syndrome patients were divided into three classes: 71 cases (47.33%) of syndrome of qi deficiency of spleen and kidney, 70 cases (46.67%) of syndrome of phlegm-dampness due to spleen deficiency, 9 cases (6.00%) of spleen-kidney deficiency pattern. Conclusion In Lincang area of Yunnan Province, the syndrome of acquired immunodeficiency syndrome is mixed with deficiency and solid syndrome, mainly deficiency syndrome, qi deficiency is the main pathogenesis, phlegm and dampness is the main pathological factor, and the disease location is mainly in spleen and kidney
王兴1,2 周青1 李钦1 叶芳3 曲源3 温伟波4. 基于潜在类别模型的云南临沧艾滋病中医证候分布研究[J]. 中国医药导报, 2021, 18(28): 139-143,155.
WANG Xing1,2 ZHOU Qing1 LI Qin1 YE Fang3 QU Yuan3 WEN Weibo4. Study of distribution of traditional Chinese medicine syndromes of acquired immunodeficiency syndrome in Lincang, Yunnan based on latent class model. 中国医药导报, 2021, 18(28): 139-143,155.
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