Abstract：Objective To investigate the effect of small dose Dexmedetomidine in the recovery period of general anesthesia in children with obstructive sleep apnea-hypopnea syndrome (OSAHS) tonsillectomy, and to provide reference for clinical selection of anesthesia program. Methods A total of 100 children with OSAHS who underwent tonsillectomy in Fuyang People’s Hospital, Anhui Province from January 2018 to December 2019 were selected as study subjects. According to the random number table method, they were divided into observation group (50 cases) and control group (50 cases). Children of two groups used the same anesthesia induction and maintenance plan. Control group was given 1 μg/kg Dexmedetomidine intraoperatively, and observation group was given 0.5 μg/kg Dexmedetomidine intraoperatively. Ramsay sedation score after extubation, postoperation visual analogue score (VAS), recovery and adverse reactions in the recovery period were compared between two groups. Results There were no significant differences in Ramsay sedation score after extubation and postoperation VAS score between two groups (P > 0.05). The respiratory recovery time, consciousness recovery time and extubation time in the recovery period in observation group were shorter than those in control group, and the differences were highly statistically significant (P < 0.01). The total incidence of adverse reactions in observation group was lower than that in control group in the recovery period, and the difference was statistically significant (P < 0.05). Conclusion Dexmedetomidine 0.5 μg/kg has good sedation and analgesia effect during the recovery period of general anesthesia after OSAHS tonsillectomy in children, and compared with 1.0 μg/kg Dexmedetomidine, patients have quicker recovery of respiration and consciousness, and fewer adverse reactions.
任荣1 邓海波1 李真1 蔡宁1 张新海2. 小剂量右美托咪定在小儿OSAHS扁桃体切除术全麻苏醒期的应用[J]. 中国医药导报, 2021, 18(28): 121-124.
REN Rong1 DENG Haibo1 LI Zhen1 CAI Ning1 ZHANG Xinhai2. Application of small dose Dexmedetomidine in the recovery period of general anesthesia in children with OSAHS tonsillectomy. 中国医药导报, 2021, 18(28): 121-124.
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