Abstract：Objective To investigate the influencing factors of retinoblastoma (RB) children’s family members’ compliance with interventional surgery. Methods A total of 500 children with RB admitted to Xinhua Hospital Affiliated to School of Medicine of Shanghai Jiao Tong University (hereinafter referred to as “our Hospital”) from January to December 2020 were selected as the research objects, and one family member from each family was selected as the key objects. The compliance questionnaire made by our hospital was used to evaluate the compliance of all the children’s family members to the interventional surgery. According to the results, the children’s family members were divided into poor compliance group (＜ eight points, 42 cases) and good compliance group (≥ eight points, 458 cases). The baseline data of the children and their families were recorded and compared in detail, and the factors influencing the poor compliance of family members of RB children with interventional surgery were screened by univariate and multivariate analysis. Results The proportion of leucocoria and the proportion of monthly family income ≥5000 yuan in poor compliance group were lower than those in good compliance group, and the differences were statistically significant (P ＜ 0.05). There were statistically significant differences in educational level and anxiety level between the two groups (P ＜ 0.05). Leucocoria and moderate and severe anxiety were independent risk factors for poor compliance with interventional surgery in the families of children with RB (OR ＞ 1, P ＜ 0.05), while the educational level of the family members was technical secondary school or high school or above, and the family income ≥5000 yuan was the protective factors (OR ＜ 1, P ＜ 0.05). Conclusion RB children with leucocoria as the main symptom, and moderate and severe anxiety may lead to poor compliance of family members to interventional surgery, which should be paid attention to.
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