Abstract：Objective To investigate the effect of accelerated rehabilitation surgical intervention on postoperative outcomes in patients with laparoscopic advanced colorectal cancer. Methods A total of 85 patients with advanced colorectal cancer in Fuyang People’s Hospital of Anhui Province from October 2017 to January 2020 were selected, and they were divided into the experimental group (43 cases) and the control group (42 cases) according to random number table method. The experimental group received laparoscopic advanced colorectal cancer radical resection + accelerated rehabilitation surgical intervention, while the control group received laparoscopic advanced colorectal cancer radical resection + routine intervention. The first exhaust, getting out of bed, defecation and postoperative hospital stay were compared between the two groups; the levels of hemoglobin (Hb) and albumin (ALB) before surgery and seven days after surgery were compared between the two groups; the pain level of the two groups were compared 6 and 48 h after operation; EORTC QLQ-C30 was used to score the quality of life before surgery and one month after surgery; and the occurrence of complications and satisfaction were recorded in the two groups. Results The first exhaust time, getting out of bed time, defecation time and postoperative hospital stay in the experimental group were shorter than those in the control group (P < 0.05). Before surgery, there were no significant differences in the levels of ALB and Hb between the two groups (P > 0.05). Seven days after surgery, the levels of ALB and Hb in the experimental group were higher than those in the control group (P < 0.05). The visual analogue scale score of the experimental group was lower than that of control group 6 and 48 h after surgery (P < 0.05). Before surgery, there was no significant difference in EORTC QLQ-C30 score between the two groups (P > 0.05), one month after surgery, the scores of physical, emotional, role, cognitive and social function in the experimental group were higher than those in the control group (P < 0.05). The total incidence of postoperative complications in the experimental group was lower than that in the control group (P < 0.05). There was no significant difference in postoperative satisfaction between the two groups (P > 0.05). Conclusion The application of accelerated rehabilitation surgical intervention in laparoscopic advanced colorectal cancer resection can shorten exhaust time and hospital stay, reduce the postoperative pain and complications rate, and improve quality of life and satisfaction.
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