Abstract：Objective To observe the efficacy of Zhitong Huazheng Capsules combined with Ceftazidime for Injection in the treatment of chronic pelvic inflammatory disease. Methods A total of 100 patients with chronic pelvic inflammatory disease from Jinan Fourth People’s Hospital from February 2019 to October 2020 were selected. According to the random number table method, they were divided into control group and observation group, with 50 cases in each group. Control group received intravenous infusion of Ceftazidime for Injection, observation group was treated with Zhitong Huazheng Capsules on the basis of control group, both groups were treated for 14 days. The efficacy, pain, pelvic inflammatory mass diameter, high-sensitivity C-reactive protein (hs-CRP), human transforming growth factor receptor β1 (TGF-β1), malondialdehyde (MDA), superoxide dismutase (SOD), and the incidence of adverse reactions were compared between two groups. Results The total effective rate of observation group was higher than that of control group (P < 0.05). After 14 days of treatment, the levels of hs-CRP and MDA in two groups were lower than those before treatment, and observation group was lower than control group (P < 0.05); the levels of TGF-β1 and SOD in two groups were higher than those before treatment, and observation group were higher than control group (P < 0.05). After 14 days of treatment, visual analogue scale score in two groups were lower than those before treatment, and observation group was lower than control group (P < 0.05); the pelvic inflammatory mass diameter in two groups were smaller than those before treatment, and observation group was smaller than control group (P < 0.05). There was no significant difference in the total incidence of adverse reactions between two groups (P > 0.05). Conclusion Zhitong Huazheng Capsules combined with Ceftazidime for Injection in the treatment of chronic pelvic inflammatory disease can effectively reduce oxidative stress, reduce the level of inflammatory factors, improve clinical symptoms, it is safe and reliable.
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