Analysis on the medication rule of traditional Chinese medicine in the treatment of vertigo based on traditional Chinese medicine inheritance auxiliary platform
LIN Ling1 YUAN Jie2 LIU Dongling2 HAN Zucheng2 LUO Fan1 WANG Ying1 CHEN Jie2
1.The First Clinical College, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.Department of Encephalopathy, Shaanxi Traditional Chinese Medicine Hospital, Shaanxi Province, Xi’an 710003, China
Abstract：Objective To explore the medication rules of traditional Chinese medicine in the treatment of vertigo by using traditional Chinese medicine inheritance auxiliary platform. Methods The related literatures on the treatment of vertigo with traditional Chinese medicine from May 2015 to May 2020 in CNKI were searched. The theme with “vertigo” or “dizziness” and “Chinese medicine” or “traditional Chinese medicine” was advanced searched. The prescription was screened and the database was built. The frequency of drug use and drug pairs use, association rules and prescription rules were analyzed. Results Finally, 234 prescriptions were included, involved 235 kinds of traditional Chinese medicine, and the high-frequency drugs were Atractylodis Macrocephalae Rhizoma, Poria, Gastrodiae Rhizoma, Chuanxiong Rhizoma and Angelicae Sinensis Radix. The most commonly used traditional Chinese medicines were tonifying deficiency drugs, diuretic drugs, calming liver and calming wind drugs, promoting blood circulation and removing blood stasis drugs, etc. In terms of drug properties, the four qi was mainly warm and cold, the five flavors was mainly sweet and pungent, and the meridian tropism was mainly liver and spleen meridians. High frequency drug combinations included “Atractylodis Macrocephalae Rhizoma and Poria” “Atractylodis Macrocephalae Rhizoma and Gastrodiae Rhizoma” “Poria and Gastrodiae Rhizoma”, etc. Among the association rules between drugs, “Citri Reticulatae Pericarpium -> Atractylodis Macrocephalae Rhizoma” had the strongest association. Twelve core combinations and six new prescriptions were found. Conclusion Through excavation and analysis, it is concluded that the treatment of vertigo mainly includes regulating qi and activating blood circulation, drying dampness and resolving phlegm, calming liver yang, tonifying qi and blood, nourishing yin and kidney, which is in line with the principle of treating both symptoms and signs of traditional Chinese medicine. Its core combination and new prescription can provide reference for clinical medication and new drug research and development.
林玲1 袁捷2 刘冬玲2 韩祖成2 骆凡1 王莹1 陈杰2. 基于中医传承辅助平台挖掘中医药治疗眩晕的用药规律[J]. 中国医药导报, 2021, 18(18): 146-150.
LIN Ling1 YUAN Jie2 LIU Dongling2 HAN Zucheng2 LUO Fan1 WANG Ying1 CHEN Jie2. Analysis on the medication rule of traditional Chinese medicine in the treatment of vertigo based on traditional Chinese medicine inheritance auxiliary platform. 中国医药导报, 2021, 18(18): 146-150.
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