Prognostic effect of laparoscopic extensive hysterectomy combined with pelvic lymph node resection on early cervical cancer and the influence of pelvic floor muscle function
WANG Qian1 CHEN Yan2 CHEN Hongmei1
1.Department of Gynecology and Obstetrics, Bozhou Hospital of Traditional Chinese Medicine, Anhui Province, Bozhou 236800, China;
2.Department of Gynecology and Obstetrics, the First Affiliated Hospital of Anhui Medical University, Anhui Province, Hefei 230031, China
Abstract:Objective To explore the prognostic effect of laparoscopic extensive hysterectomy combined with pelvic lymph node resection on early cervical cancer and the influence of pelvic floor muscle function. Methods Retrospective analysis was made on the clinical data of 80 patients with early cervical cancer who underwent surgical treatment were selected in Department of Gynecology and Obstetrics, Bozhou Hospital of Traditional Chinese Medicine, Anhui Province from December 2016 to December 2019. According to surgical methods, they were divided into observation group and control group, with 40 cases in each group. Observation group was treated with laparoscopic extensive hysterectomy combined with pelvic lymph node resection, while control group was treated with conventional laparotomy extensive hysterectomy combined with pelvic lymph node resection. After the operation, the patients were followed up, the functional assessment of cancer therapy-general (FACT-G) score, half a year and one year survival rate after surgery, recurrence rate within one year after surgery, normal rate of pelvic floor muscle strength, female sexual function index (FSFI) score and incidence of sexual dysfunction were compared between two groups. Results One year after surgery, FACT-G score of observation group was higher than that of control group, and the difference was highly statistically significant (P < 0.01). There were no significant differences between two groups in half a year, one year survival rate after surgery, and recurrence rate within one year after surgery (P > 0.05). The normal rate of pelvic floor muscle strength and FSFI score in observation group were higher than those in control group, and the differences were statistically significant (P < 0.05 or P < 0.01); the incidence of sexual dysfunction was lower than that of control group, and the difference was highly statistically significant (P < 0.01). Conclusion Laparoscopic extensive hysterectomy combined with pelvic lymph node resection in the treatment of early cervical cancer has the same prognosis as laparotomy. The patients’ quality of life is significantly improved, and the pelvic floor function is well recovered after operation, which is worthy of clinical application.
王倩1 陈炎2 陈红梅1. 腹腔镜下广泛子宫切除术联合盆腔淋巴结切除治疗早期宫颈癌的预后效果及对盆底肌功能的影响[J]. 中国医药导报, 2021, 18(18): 103-106.
WANG Qian1 CHEN Yan2 CHEN Hongmei1. Prognostic effect of laparoscopic extensive hysterectomy combined with pelvic lymph node resection on early cervical cancer and the influence of pelvic floor muscle function. 中国医药导报, 2021, 18(18): 103-106.