Abstract：Objective To explore the predictive value of four-dimensional Doppler ultrasound in early pregnancy of fetal growth restriction (FGR). Methods A total of 367 normal single pregnant women who delivered in Tangshan Maternal and Child Health Hospital from March 2019 to March 2020 were selected as the research subjects. During nuchal translucency examination, placental energy Doppler volume data were collected by four-dimensional energy Doppler ultrasonography, and vascularization index (VI), vascularization-blood flow index (VFI) and blood flow index (FI) were calculated by GE 4D View software. All pregnant women were followed up by telephone until birth, according to the diagnosis results, they were devided into FGR group (59 cases) and control group (308 cases). Placental volume (PV), placental quotient (PQ), left uterine artery pulse index (PI), right uterine artery PI, umbilical artery systolic/diastolic velocity ratio (S/D), PI of middle cerebral artery and four-dimensional energy Doppler ultrasound parameters VI, VFI, FI were compared between two groups, and the pregnancy prognosis of two groups were observed. Results PV, PQ and PI of middle cerebral artery in FGR group were lower than those in control group, while left uterine artery PI, right uterine artery PI and S/D of umbilical artery in FGR group were higher than those in control group (all P < 0.01). VI, FI and VFI of FGR group were lower than those of control group (all P < 0.01). Apgar score of FGR group was lower than that of control group (P < 0.01); there were no significant differences in the incidence of fetal distress and neonatal asphyxia between two groups (P > 0.05). Conclusion Four-dimensional energy Doppler ultrasound detection in early pregnancy is of great value for the early prediction of FGR. VI and VFI indexes are sensitive indicators for the evaluation of FGR in early pregnancy, and have high clinical diagnostic value.
京公网安备 11010502046598号