Psychological stress status and personality characteristics of patients with artificial insemination with husband’s semen and its relationship with the success rate of fertilization
YANG Lin ZHANG Jing LIU Yan
Department of Reproductive Medicine, Fuyang People’s Hospital, Anhui Province, Fuyang 236000, China
Abstract:Objective To observe the psychological stress and personality characteristics of patients with husband’s artificial insemination, to analyze the relationship between psychological stress and personality characteristics and the success of fertilization. Methods The clinical data of 127 infertility patients who underwent husband’s artificial insemination in Fuyang People’s Hospital from January 2018 to January 2020 were retrospectively collected. According to the success or failure of fertilization, they were divided into successful group (33 cases) and failure group (94 cases). The psychological stress status (assessed by the life event scale [LES]) and personality characteristics (assessed by the Eysenck personality questionnaire [EPQ], including the validity scale [L], the psychopath scale [P], the emotional scale [N] and the internal and external tendency scale [E]) of the two groups were observed, while the relationship between psychological stress status and personality characteristics and the success of artificial insemination patients were analyzed. Results There was no statistically significant difference between the two groups of positive life events on the LES scale (P > 0.05). The scores of negative life events and total life events on the LES scale of the failure group were higher than those of the successful group, and the differences were statistically significant (P < 0.05). The comparison of L score, P score and E score between the two groups of EPQ were not statistically significant (P > 0.05); while the N score of the failure group was higher than that of the successful group, and the differences were statistically significant (P < 0.05). Negative life events, total life events, and N scores were the influencing factors for the fertilization success of artificial insemination patients (OR = 1.297, 1.369, 2.453, P < 0.05). Conclusion Patients with artificial insemination of husband’s sperm generally have different degrees of psychological stress and bad personality characteristics, which may have a certain negative impact on the success rate of fertilization of patients with husband’s artificial insemination. Clinically, the psychological stress status and personality characteristics of patients with artificial insemination of husband’s sperm should be evaluated as soon as possible. Propose reasonable interventions to help patients improve their psychological stress and personality characteristics, which is of great significance for improving the fertilization success rate of artificial insemination patients.
杨琳 张静 刘燕. 夫精人工授精患者心理应激状况和人格特征及其与受精成功率的关系[J]. 中国医药导报, 2021, 18(8): 54-57.
YANG Lin ZHANG Jing LIU Yan. Psychological stress status and personality characteristics of patients with artificial insemination with husband’s semen and its relationship with the success rate of fertilization. 中国医药导报, 2021, 18(8): 54-57.
[1] Kop PA,van Wely M,Mol BW,et al. Intrauterine insemination or intracervical insemination with cryopreserved donor sperm in the natural cycle:a cohort study [J]. Hum Reprod,2015,30(3):603-607.
[2] 邢慧琴,李艳梅,孔庆萍,等.辅助生殖技术治疗后自然流产相关因素分析探究[J].山西医药杂志,2018,47(22):2687-2688.
[3] 朱娟,马燕琳,黄元华,等.2140例不孕患者夫精宫腔内人工授精的临床效果及其影响因素[J].山东医药,2017, 57(19):1-4.
[4] Mutlu I,Erdem M,Erdem A. The impact of the modified speculum application technique on the success rates of intrauterine insemination:A randomized controlled study [J]. Taiwan J Obstet Gynecol,2019,58(3):370-374.
[5] Kroemeke A,Kubicka E. Positive and negative adjustment in couples undergoing infertility treatment:The impact of support exchange [J]. PLoS One,2018,13(6):e0200124.
[6] 蔡素平,林婷,叶钊锋,等.早期记忆的情绪特点及其与人格特征的关系[J].现代预防医学,2012,39(23):6216-6218.
[7] 谢幸,苟文丽.妇产科学[M].8版.北京:人民卫生出版社,2013:456-457.
[8] 陈宏.乳腺癌患者心理社会因素与术前应激特征及其对免疫功能影响[D].苏州:苏州大学,2002:4-5.
[9] Sato T. The Eysenck Personality Questionnaire Brief Version:factor structure and reliability [J]. J Psychol,2005, 139(6):545-552.
[10] Malina A,B?覥aszkiewicz A,Owczarz U. Psychosocial aspects of infertility and its treatment [J]. Ginekol Pol,2016,87(7):527-531.
[11] 苑杰,贾娜娜,庞静娟,等.不孕不育患者抑郁焦虑情绪影响因素研究进展[J].中国医药导报,2016,13(15):48-51.
[12] Bai F,Wang DY,Fan YJ,et al. Assisted reproductive technology service availability,efficacy and safety in mainland China:2016 [J]. Hum Reprod,2020,35(2):446-452.
[13] 杨丛品,王丽丽,李爱民.不孕妇女心理应激状态对IVF-ET妊娠结局的影响[J].河北医科大学学报,2018,39(7):806-809.
[14] MacKinnon AL,Yang L,Feeley N,et al. Birth setting,labour experience,and postpartum psychological distress [J]. Midwifery,2017,33(50):110-116.
[15] 龙玲,李静,彭倩,等.女性不孕症患者心理弹性、社会支持与生育应激的相关研究[J].重庆医学,2015,44(3):426-427,432.
[16] 韩洁,刘子怡,袭著革,等.心理应激对女性生殖内分泌系统的影响[J].生理科学进展,2020,51(1):29-32.
[17] Haemmerli Keller K,Alder G,Loewer L,et al. Treatment-related psychological stress in different in vitro fertilization therapies with and without gonadotropin stimulation [J]. Acta Obstet Gynecol Scand,2018,97(3):269-276.
[18] 连玉龙,李富业,王磊,等.糖皮质激素受体和促肾上腺皮质激素受体基因多态性与应激的关系[J].中华劳动卫生职业病杂志,2011,29(12):902-907.
[19] Cesta CE,Johansson ALV,Hreinsson J,et al. A prospective investigation of perceived stress,infertility-related stress,and cortisol levels in women undergoing in vitro fertilization:influence on embryo quality and clinical pregnancy rate [J]. Acta Obstet Gynecol Scand,2018,97(3):258-268.
[20] Tola EN,Eris Yalcin S,Dugan N,et al. The association of type D personality and depression with infertility in women [J]. J Psychosom Obstet Gynaecol,2019,38(20):1-8.
[21] 徐桂华,王秋琴,柏亚妹,等.排卵障碍性不孕症病人的人格特征与心理研究[J].护理研究,2015,29(3):275-279.
[22] 徐丽,王丹萍.临床护理路径对不孕症实施人工授精患者自我效能及妊娠结局影响[J].中外医学研究,2019, 17(14):115-117.
[23] 施冬青.排卵障碍性不孕症中医治疗研究进展[J].中国医药科学,2020,10(12):42-45.
[24] Thomas S,Sebastian T,Karthikeyan M,et al. Effectiveness of spontaneous ovulation as monitored by urinary luteinising hormone versus induced ovulation by administration of human chorionic gonadotrophin in couples undergoing gonadotrophin-stimulated intrauterine insemination:a randomised controlled trial [J]. BJOG,2019, 126(4):58-65.
[25] Silva JF,Ocarino NM,Serakides R. Thyroid hormones and female reproduction [J]. Biol Reprod,2018,99(5):907-921.
[26] So S,Yamaguchi W,Murabayashi N,et al. Effect of moderately increased thyroid-stimulating hormone levels and presence of thyroid antibodies on pregnancy among infertile women [J]. Reprod Med Biol,2019,19(1):82-88.
[27] 张鑫,刘丽英,赵彬,等.女性不孕症患者生育生活质量影响因素的研究及护理体会[J].中国当代医药,2020, 27(27):147-150.
[28] 罗丽燕,史莉,赵阳,等.接受供精人工授精夫妇生育压力和生活质量研究[J].国际生殖健康/计划生育杂志,2019,38(3):201-205.