Abstract:Objective To study the effect of ultrasound-guided iliohypogastric/ilioinguinal nerve block on postoperative analgesia after cesarean section. Methods From April 2019 to March 2020, 80 pregnant women who had cesarean section in Huangshan Shoukang Hospital of Anhui Province were selected for the study. They were divided into control group and experimental group according to random number table, 40 cases in each group. Control group was given patient-controlled intravenous analgesia, and experimental group was given ultrasound-guided iliohypogastric/ilioinguinal nerve block analgesia on the basis of control group. Visual analogue scale (VAS) six hours before operation and 12 hours after operation, times of pressing analgesia pump, time of first exhaust and recovery rate of analgesia, serum prolactin level at different time points and colostrum time in two groups were analyzed. The incidence of adverse reactions was compared between two groups. Results At 12 hours after operation, VAS of two groups was lower than that of six hours before operation, and VAS of experimental group was lower than that of control group, the difference was statistically significant (P < 0.05). The times of pressing analgesia pump in experimental group were less than those in control group within 24 hours after operation, the first exhaust time of experimental group was shorter than that of control group, and the analgesic recovery rate of experimental group was lower than that of control group, the difference was statistically significant (P < 0.05). Twenty four hours after operation, the serum prolactin levels of two groups were higher than that of one day before operation, and the serum prolactin level of experimental group was higher than that of control group, the difference was statistically significant (P < 0.05). The colostrum time of experimental group was shorter than that of control group (P < 0.05). There was no significant difference in the total incidence of adverse reactions between two groups within 24 hours (P > 0.05). Conclusion Ultrasound-guided iliohypogastric/ilioinguinal nerve block can effectively relieve postoperative pain and promote gastrointestinal function recovery and early lactation, it is worth popularizing and applying.