1.Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210029, China;
2.Department of Emergency, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210029, China
Abstract：Objective To research and establish the quality standard of Shengjiang Pills. Methods Thin layer chromatography (TLC) was used to identify Rhizoma Curcumae Longae and Radix et Rhizoma Rhei in Shengjiang Pills. High performance liquid chromatography was used to determine the contents of aloe-emodin, rhein, emodin, chrysophanol, and physcion in Shengjiang Pills. Results The characteristic spots were obvious, the resolution was good, and the negative control had no interference by TLC. The average contents of aloe-emodin, rhein, emodin, chrysophanol, and physcion in three batches of Shengjiang Pills were respectively 1.19, 0.64, 2.77, 5.12, 0.85 mg/g. In the range of 6.37-108.90 μg/mL (r = 0.9997), 6.73-115.00 μg/mL (r = 0.9994), 6.96-119.00 μg/mL(r = 0.9997), 6.96-119.00 μg/mL (r = 0.9999), 3.32-56.80 μg/mL (r = 0.9998), respectively, and had a good linear relationship with the integral value of peak area. The average recovery rates were 89.91% (RSD = 2.12%), 92.87% (RSD = 1.06%), 91.24% (RSD = 1.67%), 93.50% (RSD = 2.31%), 88.64% (RSD = 2.46%). Conclusion The method established in this experiment has good reproducibility, easy to operate, accuracy and reliability, and can be applied to the quality control of Shengjiang Pills.
陆超1 奚肇庆2 吴磊1 田立元1▲. 升降丸质量标准研究[J]. 中国医药导报, 2020, 17(31): 4-7.
LU Chao1 XI Zhaoqing2 WU Lei1 TIAN Liyuan1▲. Study on quality standard of Shengjiang Pills. 中国医药导报, 2020, 17(31): 4-7.
2020, Vol. 17 
京公网安备 11010502046598号