Abstract:Objective To analyze the application effect of out-of-hospital home nursing intervention in outpatient preschool children with asthma. Methods A total of 360 preschool children with moderate persistent asthma who attended the Pediatric Clinic of the First Affiliated Hospital of Guangxi Medical University from November 2015 to May 2019 were divided into control group and study group according to random number table method, with 180 cases in each group. The control group was received out-of-hospital routine nursing guidance, while the research group was implemented home nursing interventions outside the hospital. The percentage of peak respiratory flow rate of the predicted value (PEF%), the percentage of forced expiratory volume in the first second (FEV1%), the children′s asthma quality of life questionnaire score (PAQLQ), and compliance sexuality, frequency of acute attacks, number of re-visits, asthma day and night symptom score were compared between two groups after six months. Results After six months of home care intervention, the PEF% and FEV1% of the two groups were higher than those when they were enrolled, while the study group were higher than those of the control group, and the differences were highly statistically significant (P < 0.01); the scores of symptom dimension activity dimension and affective function were higher than those at the time of enrollment, while the study group were higher than those of the control group, and the differences were statistically significant (P < 0.05). The differences in compliance between the two groups at different times were statistically significant (P < 0.05). The compliance of the study group for three and six months of intervention were higher than that of the control group, and the differences were statistically significant (P < 0.05). After six months of intervention in the study group, the frequency of acute asthma attacks and the frequency of revisiting doctors were less than those of the control group, and the differences were statistically significant (P < 0.05); the asthma daytime symptom score and nighttime symptom score of the study group were lower than those of the control group, and the differences were statistical significance (P < 0.05). Conclusion Out-of-hospital home care intervention can improve the compliance of children with doctors, reduce the frequency of acute attacks and the frequency of re-visiting the children, improve their quality of life, and provide reference for the prevention and treatment of chronic diseases in children.