Relationship between dynamic blood glucose and diurnal dynamic blood pressure fluctuation in patients with type 2 diabetes mellitus with hypertension
PENG Fangshu1 ZHAO Xiaoxi2 LYU Yan1 ZHANG Tong1 SONG Cheng3
1.Recuperation and Rehabilitation Center, Taihu Sanatorium of Jiangsu Province Taihu Rehabilitation Hospital of Jiangsu Province, Jiangsu Province, Wuxi 214086, China;
2.Department of Cardiovascular Medicine, Wuxi People′s Hospital, Jiangsu Province, Wuxi 214023, China;
3.Department of Laboratory, Taihu Sanatorium of Jiangsu Province Taihu Rehabilitation Hospital of Jiangsu Province, Jiangsu Province, Wuxi 214086, China
Abstract：Objective To investigate the relationship between dynamic blood glucose and diurnal dynamic blood pressure fluctuation in type 2 diabetes mellitus with hypertension. Methods From June 2015 to June 2019, 96 cases with type 2 diabetes mellitus with hypertension who admitted to Taihu Sanatorium of Jiangsu Province were selected as the study subjects. According to the blood glucose fluctuation, they were divided into hyperglycemic drift group (42 cases) and hypoglycemic drift group (54 cases). General Information, standard deviation of blood glucose (SDBG), rate of diastolic blood pressure fall (DBPF) and rate of systolic blood pressure fall (SBPF) of the two groups were compared, and the relevant factors of SBPF were analyzed by multiple linear regression, and the correlation between SDBG, DBPF and SBPF were analyzed by Spearman method. Results The duration of diabetes and SDBG in hyperglycemic drift group were higher than those in hypoglycemic drift group, while SBPF and DBPF were lower than those in hypoglycemic drift group (all P < 0.05). The duration of diabetes and SDBG were the influencing factors of SBPF (P < 0.05). In hypoglycemic drift group, SDBG was negatively correlated with DBPF and SBPF(r = -0.689,-0.579， P < 0.05). Conclusion There is a negative correlation between blood glucose fluctuation and diurnal dynamic blood pressure fluctuation in patients with type 2 diabetes mellitus with hypertension. Reducing blood glucose fluctuation in patients is conducive to maintaining blood pressure rhythm, which has certain clinical reference value in the treatment of patients with type 2 diabetes mellitus with hypertension.
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2020, Vol. 17 
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