Analysis of risk factors of acquired immunodeficiency syndrome complicated with tuberculosis infection
XU Yuping1,2 TIAN Qun2 WANG Jiye3
1.Health Center of Guilin Medical College, Guangxi Zhuang Autonomous Region, Guilin 541004, China;
2.Infectious Disease Department, Guilin Third People′s Hospital, Guangxi Zhuang Autonomous Region, Guilin 541001, China;
3.Department of Respiratory and Critical Medicine, the Second People′s Hospital of Guilin, Guangxi Zhuang Autonomous Region, Guilin 541001, China
Abstract:Objective To explore the risk factors of acquired immunodeficiency syndrome (AIDS) complicated with tuberculosis infection. Methods A total of 3224 AIDS patients admitted to Guilin Third People′s Hospital of Cuangxi Zhuang Autonomous Region from January 2015 to November 2019 were selected as the subjects. According to the presence or absence of tuberculosis infection, they were divided into infection group (255 cases) and non infection group (2969 cases). The basic data and disease-related conditions were compared between the two groups. The risk factors of AIDS complicated with tuberculosis infection were analysed by multivariate related factors. Results The proportion of patients with smoking history, low family income, unemployment and intravenous drug use in the infection group were significantly higher than those in the non infection group (P < 0.05), while the proportion of patients with BCG vaccination history were significantly lower than that in the non infection group (P < 0.05). There were no significant differences between the two groups in age, gender, drinking history, education level, marital status, urban and rural distribution (P > 0.05). Multivariate logistic regression analysis showed that smoking history, unemployment, intravenous drug use were the independent risk factors of AIDS complicated with tuberculosis infection (P < 0.05), and BCG vaccination history was the protective factor of AIDS with tuberculosis infection (P < 0.05). Conclusion Low family income, unemployment, intravenous drug use, smoking history are the independent risk factors of AIDS with tuberculosis infection, while BCG vaccination is the protective factor of AIDS with tuberculosis infection.