Abstract:Objective To investigate clinical effect of transcutaneous electric acupoint stimulation in the treatment of patients with cancer-related fatigue after chemotherapy. Methods Randomized study was used. From October 2018 to June 2019, 116 cancer patients who met the standard were screened in Oncology Department of Guangdong Provincial Hospital of Traditional Chinese Medicine. According to the random number table method, they were divided into two groups, with 58 cases in each group, 8 cases of abscission in each group, 53 cases in final control group and 55 cases in final experimental group. Control group was given routine diagnosis and treatment nursing in Oncology Department, On this basis, experimental group was treated with transcutaneous acupoint electrical stimulation. zhōngw?觍n, qìh?觍i, gu?觀nyu?觃n, bilateral neìgu?觀n, bilateral zús?觀nlǐ and bilateral s?觀nyīnji?觀o acupoints were selected. They were treated during and before chemotherapy, 20 minutes one time, once a day, for 5 days. Treatment period of two groups was 5 days. The fatigue state and quality of life of the patients were evaluated by Piper fatigue revised scale and functional assessment of cancer therapy-general (FACT-G) scale before and after treatment. Results There were significant differences between two groups in scores of overall and all dimensions of Piper fatigue revised scale after treatment (P < 0.05). In control group, overall scores and emotional fatigue score of Piper fatigue revised scale after treatment were higher than those before treatment, and in experimental group, overall score and all dimensions scores of Piper fatigue revised scale after treatment were lower than those before treatment, the differences were statistically significant (P < 0.05). There were significant differences between two groups in total scores of FACT-G and physiological status scores after treatment (P < 0.05). In experimental group, the score of physiological condition was lower than that before treatment, and the score of functional condition was higher than that before treatment; total score of FACT-G and the score of physiological status in control group were lower than those before treatment, and the score of functional status was higher than that before treatment, the differences were statistically significant (P < 0.05). Conclusion Transcutaneous electric acupoint stimulation can alleviate cancer-related fatigue and improve the quality of life of tumor patients after chemotherapy.
李艳 张海波 刘译鸿 张馥丽 胡利敏 刘焕仪 袁莉 李海旭. 经皮穴位电刺激治疗化疗后癌因性疲乏的临床效果[J]. 中国医药导报, 2020, 17(12): 149-152,168.
LI Yan ZHANG Haibo LIU Yihong ZHANG Fuli HU Limin LIU Huanyi YUAN Li LI Haixu. Clinical effect of transcutaneous electric acupoint stimulation in the treatment of cancer-related fatigue after chemotherapy. 中国医药导报, 2020, 17(12): 149-152,168.
[1] NCCN Clinical Practice Guidelines in Oncology-Cancer-Related Fatigue(Version Ⅰ. 2017) [DB/OL]. http://www.nccn.org.
[2] Hofman M,Ryan JL,Figueroa-Moseley CD,et al. Cancer-related fatigue:the scale of the problem [J]. Oncologist,2007,12(Suppl 1):4-10.
[3] Henry DH,Viswanathan HN,Elkin EP,et al. Symptoms and treatment burden associated with cancer treatment:results from a cross-sectional national survey in the US [J]. Support Care Cancer,2008,16(7):791-801.
[4] He XR,Wang Q,Li PP. Acupuncture and moxibustion for cancer-related fatigue:a systematic review and meta-analysis [J]. Asian Pac J Cancer Prev,2013,14(5):3067-3074.
[5] 黄菲,赵焰.经皮穴位电刺激治疗癌因性疲乏的随机对照试验研究[J].中国康复医学杂志,2019,34(6):688-692.
[6] 孙秋子.简易式经皮穴位电刺激缓解肿瘤患者癌因性疲乏的效果[J].中华现代护理杂志,2011,17(29):3486-3488.
[7] 中国抗癌协会.新编常见恶性肿瘤诊治规范(合订本)[M].北京:中国协和医科大学出版社,1999:773.
[8] 薛秀娟,许翠萍,杨雪莹,等.癌因性疲乏测评工具及评价指标的研究进展[J].中华护理杂志,2012,47(9):859-861.
[9] 万崇华,孟琼,汤学良,等.癌症患者生命质量测定量表FACT-G中文版评介[J].实用肿瘤杂志,2006,21(1):77-80.
[10] Yeh MH,Chao CH,Koo M,et al. Association of traditional Chinese medicine body constitution and moderate-to-severe cancer-related fatigue in cancer patients [J]. Complement Ther Med,2019,43:44-48.
[11] Ancoli-Israel S,Liu L,Rissling M,et al. Sleep,fatigue,depression,and circadian activity rhythms in women with breast cancer before and after treatment:a 1-year longitudinal study [J]. Support Care Cancer,2014,22(9):2535-2545.
[12] 张红娟,许海荣,李巧梅,等.影响胃癌化疗期间患者癌性疲乏发生的危险因素分析及自我管理模式的干预效果研究[J].现代肿瘤医学,2019,27(23):4238-4242.
[13] 曹丹,杨薇,罗文燕,等.肺癌化疗患者癌因性疲乏的调查分析[J].解放军医药杂志,2018,30(9):16-19.
[14] 周洁琼,陈祥建.自我管理教育对女性结直肠癌患者围手术期癌因性疲乏及生命质量的影响分析[J].中国现代医生,2018,56(31):80-83,86.
[15] 刘旻,任中贤,姚丽萍,等.患者微信群结合奥马哈系统模式的延续护理对肺癌癌因性疲乏的影响[J].中国现代医生,2018,56(15):149-152.
[16] 李琼,涂朝勇.正念减压疗法对肝癌介入化疗栓塞患者癌因性疲乏和睡眠质量的改善作用[J].中国现代医生,2019,57(6):59-62.
[17] 叶华清.淋巴瘤化疗伴癌因性疲乏患者实施护理干预后的效果观察[J].中国医药科学,2018,8(19):115-117,196.
[18] Liao M,Xie Y,Yan J,et al. Effect of acupuncture at 3 anti-fatigue acupoints in the treatment of cancer-related fatigue in patients with cancer:protocol for a systematic review and meta-analysis of randomized controlled trials [J]. Medicine,2019,98(23):e15919.
[19] Arring NM,Barton DL,Brooks T,et al. Integrative therapies for cancer-related fatigue [J]. Cancer J,2019,25:349-356.
[20] Baydoun M,Barton DL,Peterson M,et al. Yoga for cancer-related fatigue in survivors of hematopoietic cell transplantation:a feasibility study [J]. J Pain Symptom Manage,2020,59(3):702-708.
[21] 胡彩琼.经络热度感测-背俞穴疗法在癌因性疲劳中的临床研究[D].广州:广州中医药大学,2016.
[22] 苏雅.针刺补虚组穴治疗癌因性疲乏的临床研究[D].合肥:安徽中医药大学,2016.
[23] 罗梓萍,宋梦初,费亚平.足三里穴位注射治疗38例恶性肿瘤的临床观察[J].中国民间疗法,2017(10):22-23.
[24] Nilsson M,Arving C,Thormodsen I,et al. Moderate-to-vigorous intensity physical activity is associated with modified fatigue during and after cancer treatment [J]. Support Care Cancer,2019. [Epub ahead of print].