Abstract：Objective To investgate the effect of concentrated Naikan therapy on implicit cognition bias in Alcohol dependent patients using go/no-go association task (GNAT). Methods From October 2013 to December 2015, 28 patients met the criteria of alcohol dependence were enrolled as research group and matched sexual, age and education degree of 28 healthy persons were enrolled as control group. The research group was treated with concentrated Naikan therapy for 4 weeks. The right rate, response time and false rate were measured and compared by GNAT between the two groups. Results In the control group, there were no significant differences in right rate, response time and false rate between before and after treatment in test 1 and test 2 (P ＞ 0.05). Before treatment, in the research group test 1, the response time was shorter, the right rate was higher and the false rate was lower than those of control group, with statistically significant differences (P ＜ 0.05); in the research group test 2, the response time was longer, the right rate was lower and the false rate was higher than those of control group, with statistically significant differences (P ＜ 0.05). After treatment, in the research group test 1, the response time was longer, the right rate was lower and the false rate was higher than those of before treatment, with statistically significant differences (P ＜ 0.05); in the research group test 2, the response time was longer, the right rate was higher and the false rate was lower than those of before treatment, with statistically significant differences (P ＜ 0.05). Conclusion Concentrated Naikan therapy can improve the implicit cognition of patients with alcohol dependent, which might be a useful methods for preventing the re-drinking behavior.
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