Abstract:Peritoneal metastasis of gastric cancer has high incidence and short survival time, which is one of the main causes of death in advanced gastric cancer. In spite of several advances have been made in diagnosis and treatment, the prognosis of patients with peritoneal metastasis is still lower. Effective preventive measures are as important as treatment of peritoneal metastasis. Hyperthemic intraperitoneal perfusion chemotherapy, extensive intraoperative peritoneal lavage, early postoperative intraperitoneal chemotherapy and postoperative adjuvant chemotherapy can improve the prognosis of patients with peritoneal metastasis in high-risk groups. The systemic chemotherapy is the main treatment for peritoneal metastasis of gastric cancer, which can be combined with a variety of treatment methods, including intraperitoneal chemotherapy, targeted therapy and immunotherapy. In particular, the conversion therapy can significantly improve the prognosis of gastric cancer patients with peritoneal metastasis. However, the selection of the groups, the regimens and the timing of the conversion therapy are still the current focus and difficulty. This article summarizes the research status of treatment for peritoneal metastasis of gastric cancer in recent years, thus providing some references for the clinical practice.
韩博涵 吕慧芳 陈小兵. 胃癌腹膜转移治疗的研究进展[J]. 中国医药导报, 2020, 17(4): 28-31,39.
HAN Bohan LYU Huifang CHEN Xiaobing. Research progress on the treatment of peritoneal metastasis of gastric cancer. 中国医药导报, 2020, 17(4): 28-31,39.
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