Research progresses in resting-state functional magnetic resonance in primary insomnia
GUAN Qiuli1,2 GUO Jing1,3▲
1.Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China;
2.Clinical Medical College of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China;
3.Beijing Key Laboratory of Nerve Regulation of Acupuncture and Moxibustion, Beijing 100010, China
Abstract:The pathogenesis of insomnia is still unclear. Resting-state functional magnetic resonance (rs-fMRI) provides a powerful technical support for further exploring the changes of brain function in insomnia. In this paper, rs-fMRI studies on primary insomnia in recent years were reviewed and summarized. The results found that abnormal brain areas were mainly located in cognitive-emotional related brain areas such as insula, prefrontal lobe, temporal lobe and limbic system, and there were abnormal internal activities and connections of default network and prominence network. Insomnia is closely related to negative emotions and leads to cognitive impairment and hyperarousal.
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