Imaging characteristics of lung-cancer associated acute ischemic stroke
LIN Jiacai1 WU Siting1 LIU Hui2 CUI Fang1 XU Rui2 SHAO Xue1 SHI Qiang1
1.Department of Neurology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province, Sanya 572013, China;
2.Department of Oncology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province, Sanya 572013, China
Abstract:Objective To study the imaging characteristics of lung-cancer associated acute ischemic stroke (LCA-AIS). Methods A total of 46 patients with LCA-AIS diagnosed in Hainan Hospital of Chinese PLA General Hospital from January 2014 to December 2018 were enrolled. The basic information, test data and imaging data of patients were collected and inputted for systematic analysis. Results The adenocarcinoma was more common in LCA-AIS patients with lung cancer pathology (69.57%), and the number of LCA-AIS patients in lung cancer stage Ⅳ was significantly more than the other lung cancer stages. Combined with imaging examination and laboratory results, it was found that there was a significant positive correlation between D-D polymer concentration and the number of areas involved in intracranial infarction lesions (r = 0.57, P < 0.001). The imaging manifestations of patients with LCA-AIS were diverse. After classifying the imaging manifestations, it was found that intracranial multi-focal type accounted for 60.87%, single-artery type accounted for 26.09%, and multi-artery type in the same drainage area accounted for 13.04%. The diffusion weighted imaging sequence of craniocerebral imaging examination indicated that acute infarction occurred in different stages in 21 patients (45.65%), among which 2 patients were classified as multi-artery type in the same drainage basin, and 19 patients were classified as multi-focal type in the intracranial. Conclusion The imaging manifestations of LCA-AIS patients are unique, and it is possible to identify the target patients early through imaging characteristics
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