Abstract：Objective To systematically evaluate the clinical efficacy of Duhuo Jisheng Decoction in the treatment of lumbar disc herniation (LDH). Methods The randomized controlled trial (RCT) of the treatment of LDH by Duhuo Jisheng Decoction in Chinese databases such as Wanfang, CNKI, VIP and SinoMed was searched. The retrieval time was from the establishment of the database to January 30, 2019. Meta-analysis was conducted with Review Manager 5.3 software. The observation group was treated with Duhuo Jisheng Decoction plus or minus, while the control group was treated with traction, acupuncture, Fenna chlorate capsule, Meroxicam and epidural closure. Total effective rate, visual analogue score (VAS) and adverse reactions were included in outcome indexes. Results A total of 449 articles were retrieved, 13 articles were selected and included, and 1143 patients were involved. The total effective rate of the observation group was higher than that of the control group, and the difference was highly statistically significant (OR=5.37,95%CI:3.63，7.96, P ＜ 0.01). There was no difference in the improvement of VAS score between the two groups [MD=-1.20,95%CI:-2.69，0.28, P ＞ 0.05). Adverse reactions in the observation group were less than that of the control group, and the difference was statistically significant (OR=0.15,95%CI:0.03，0.82, P ＜ 0.05). Conclusion Duhuo Jisheng Decoction can effectively alleviate the clinical symptoms of LDH patients with good safety. However, due to the shortcomings of the included literature methodology, this conclusion has some limitations and needs to be further confirmed by more high-quality clinical studies.
吴海洋 吴军豪. 独活寄生汤加减治疗腰椎间盘突出症临床效果的系统评价及Meta分析[J]. 中国医药导报, 2019, 16(30): 81-84,100.
WU Haiyang WU Junhao. A systematic review and Meta-analysis of the clinical efficacy of Duhuo Jisheng Decoction in the treatment of lumbar disc herniation. 中国医药导报, 2019, 16(30): 81-84,100.
2019, Vol. 16 
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