Abstract:So far the specific pathogenesis of enuresis in children has not been fully elucidated because of its complexity, it is accepted that central nervous system, circadian rhythm and dysfunction of bladder are mainly involved. Clinical observation finds ADHD is closely related to PNE. However, the specific relevance remains to be further studied and revealed. Recent studies show that disturbsance of metabolic pathway of dopamine transmitter and psychological factors are common risk factors of ADHD and enuresis. Sleep arousal disorders is an important reason for ADHD to cause PNE to happen. ADHD can affect the functions of the heart, liver, spleen, lung, kidney, leading to the imbalance of yin and yang in viscera, dystrophy of the sea of marrow and causing the deficiency of lung qi and spleen qi, the weakness of kidney qi, dampness-heat of the liver, heart-kidney imbalance, etc. Above pathological changes will ultimately lead to enuresis.
袁斌 钱凌. 注意力缺陷多动障碍与小儿遗尿症发病相关性的研究进展[J]. 中国医药导报, 2017, 14(34): 33-36.
YUAN Bin QIAN Ling. Research progress on the correlation between occurrence of enuresis and ADHD in children. 中国医药导报, 2017, 14(34): 33-36.
[1] 沈茜,刘小梅,姚勇,等.中国儿童单症状性夜遗尿疾病管理专家共识[J].临床儿科杂志,2014,32(10):970-975.
[2] 沈颖,刘小梅.儿童遗尿症的诊治进展[J].北京医学,2013,35(1):33-35.
[3] Yeung CK. Nocturnal enuresis(bedwetting)[J]. Curr Opin Urol,2003,13(4):337-343.
[4] Schulman SL,Stokes A,Salzman PM. The efficacy and safety of oral desmopressin in children with primary nocturnal enuresis [J]. J Urol,2001,166(6):2427-2431.
[5] Carskadon MA. Sleep deprivation:health consequences and societal impact [J]. Med Clin of North Am,2004,88(3):767.
[6] 刘中会,张国锋,张博,等.中西医结合治疗小儿原发性遗尿32例疗效观察[J].四川中医,2015,33(3):117-118.
[7] 刘树春,刘洋,宋昊,等.基于文献共词分析的肾虚证候疾病谱研究[J].世界科学技术:中医药现代化,2012,14(2):1408-1412.
[8] Van HE,De FF,De CB,et al. Internalizing and externalizing problem behavior in children with nocturnal and diurnal enuresis:a five-factor model perspective [J]. J Pediatr Psychol,2006,31(5):460-468.
[9] Baeyens D,Roeyers H,Walle JV,et al. Behavioural problems and attention-deficit hyperactivity disorder in children with enuresis:a literature review [J]. Eur J Pediatr,2005,164(11):665-672.
[10] Lottmann HB. Treatment of nocturnal enuresis in France [J]. Presse Médicale,2000,29(18):987-990.
[11] Volkmar FR. Changing perspectives on ADHD [J]. Am J Psychiatry,2003,160(6):1025-1027.
[12] 张春梅,李翠萍.儿童多动症的治疗体会[J].包头医学院学报,2013,29(2):66-67.
[13] 戴晓梅,麻宏伟,卢瑶,等.多巴胺D4受体基因启动子区多态性与原发性夜间遗尿症的关联研究[J].中国现代医学杂志,2008,18(15):2220-2222.
[14] Walle JV,Laecke EV. Pitfalls in studies of children with monosymptomatic nocturnal enuresis [J]. Pediatric Nephrology,2008,23(2):173-178.
[15] Loos M,Pattij T,Janssen MC,et al. Dopamine receptor D1/D5 gene expression in the medial prefrontal cortex predicts impulsive choice in rats [J]. Cerebral Cortex,2010, 20(5):1064.
[16] Bidwell LC,Willcutt EG,Mcqueen MB,et al. A Family Based Association Study of DRD4,DAT1,and 5HTT and Continuous Traits of Attention-Deficit Hyperactivity Disorder [J]. Behavior Genetics,2011,41(1):165-174.
[17] Tomasi D,Volkow ND. Abnormal functional connectivity in children with attention-deficit/hyperactivity disorder [J]. Biological Psychiatry,2012,71(5):443-450.
[18] Eickhoff SB,Laird AR,Grefkes C,et al. Coordinate-based activation likelihood estimation meta-analysis of neuroimaging data:a random-effects approach based on empirical estimates of spatial uncertainty [J]. Human Brain Mapping,2009,30(9):2907-2926.
[19] 邵晶晶,陈小野.小儿遗尿的主要病理是机体整体发育迟缓[J].现代中西医结合杂志,2014,23(32):3639-3641.
[20] 任桂英,钱铭怡,王玉凤,等.家庭环境与ADHD儿童某些心理特征相关性的研究[J].中国心理卫生杂志,2002, 16(4):268-272.
[21] 魏宝玉,苏林雁.家庭环境与ADHD儿童行为的相关性[J].中国临床心理学杂志,2004,12(2):145-146.
[22] Bussing R,Gary FA,Mills TL,et al. Parental explanatory models of ADHD:gender and cultural variations [J]. Soc Psychiatry Psychiatr Epidemiol,2003,38(10):563-575.
[23] 唐晖,蔡虹,翁坤荣.儿童注意缺陷多动障碍(ADHD)与微量元素铅锌的关系研究[J].微量元素与健康研究,2010,27(1):10.
[24] 黄健红,周才,司徒坚墉,等.儿童注意缺陷多动障碍与微量元素的关系[J].实用医学杂志,2008,24(14):2443-2444.
[25] 范美丽,伊长英,邹炜,等.复杂性遗尿症与微量元素锌的关系及临床意义[J].中国中西医结合儿科学,2014,6(4):319-321.
[26] Barkley RA,Fischer M,Smallish L,et al. Young adult outcome of hyperactive children:adaptive functioning in major life activities [J]. J Am Acad Child Adolesc Psychiatry,2006,45(2):192-202.
[27] Lecendreux M,Konofal E,Faraone SV. Prevalence of attention deficit hyperactivity disorder and associated features among children in France [J]. J Atten Disord,2011, 15(6):516-524.
[28] Wehmeier PM,Schacht A,Barkley RA. Social and emotional impairment in children and adolescents with ADHD and the impact on quality of life [J]. J Adolesc Health,2010,46(3):209-217.