趋化因子CXCL12及其受体CXCR4、CXCR7在子宫内膜异位症中的作用研究进展

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摘要子宫内膜异位症迄今为止病因未明。CXCL12-CXCR4/CXCR7生物轴可调节子宫内膜干细胞的增殖、迁移和侵袭，有可能成为诊治子宫内膜异位症的新靶点。本文就近年来国内外研究CXCL12-CXCR4/CXCR7生物轴在子宫内膜异位症发生和发展过程中的作用进行综述。

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	张琼刘颂平▲

关键词 ：子宫内膜异位症, CXCL12, CXCR4, CXCR7

Abstract：The etiology of endometriosis has not beeh known clearly so far. CXCL12-CXCR4/CXCR7 biological axis can regulate the proliferation, migration and invasion of endometrial stem cells, which may become a new target for diagnosis and treatment of endometriosis. This article reviews the role of CXCL12-CXCR4/CXCR7 biological axis in the occurrence and development of endometriosis at home and abroad in recent years.

Key words： Endometriosis CXCL12 CXCR4 CXCR7

基金资助:江苏省自然科学基金项目（BK20140502）；
江苏省“333”工程科研资助项目（BRA2017146）。

通讯作者: ▲通讯作者

引用本文:

张琼刘颂平▲. 趋化因子CXCL12及其受体CXCR4、CXCR7在子宫内膜异位症中的作用研究进展[J]. 中国医药导报, 2019, 16(24): 43-46.
ZHANG Qiong LIU Songping▲. Research progress of chemokine CXCL12 and its receptors CXCR4 and CXCR7 in endometriosis. 中国医药导报, 2019, 16(24): 43-46.

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http://www.yiyaodaobao.com.cn/CN/ 或 http://www.yiyaodaobao.com.cn/CN/Y2019/V16/I24/43

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