Abstract：Objective To study the diagnostic value of diffusion weighted imaging (DWI) in local recurrence for patients with rectal carcinoma after radical resection. Methods A total of 60 patients with rectal carcinoma who received radical resection in Hainan General Hospital ("our hospital" for short) from March 2016 to March 2018 and had local recurrence after surgery were selected as the recurrence group. Another 60 patients with rectal carcinoma who received radical resection in our hospital at the same time without local recurrence after surgery were enrolled as the control group. All patients were examined by conventional magnetic resonance imaging (MRI) and DWI. The results of local recurrence after radical resection in rectal carcinoma patients diagnosed by conventional MRI and DWI, signal intensity value, the levels of apparent diffusion coefficient (ADC value), contrast signal to noise ratio (CNR) were compared between recurrence group and control group. The diagnostic efficacy of conventional MRI and DWI in local recurrence of rectal carcinoma patients after radical resection were calculated by receiver operator characteristic curve (ROC). Results Conventional MRI showed that the local recurrence of rectal carcinoma patients after radical resection showed uneven thickened of intestinal wall, slightly long T1, long T2 signal, the signal on DWI sequence increased significantly and showed low signal on ADC map, and slight enhancement of scar tissue in patients without local recurrence after radical resection. The signal intensity value and CNR level of the recurrence group were higher than that of the control group, while the ADC value was lower than that of the control group, and the differences were statistically significant (P < 0.05). ROC curve analysis showed that the sensitivity of conventional MRI in the diagnosis of local recurrence after radical resection for rectal cancer was 92.00%, the specificity was 95.00%, and the area under the curve (AUC) was 0.731. The sensitivity of DWI in the diagnosis of local recurrence after rectal cancer was 96.00%, specificity was 93.00%, AUC was 0.815. The AUC of DWI was higher than that of conventional MRI, but the difference was not statistically significant (P > 0.05). Conclusion DWI has higher diagnostic value for local recurrence of rectal carcinoma patients after radical resection, and has higher diagnostic efficiency than conventional MRI. It is worthy of clinical application.
庄晓曌 李建军 符莉莉 蔡亲磊. 扩散加权成像对直肠癌患者根治术后局部复发的诊断价值[J]. 中国医药导报, 2019, 16(16): 129-133,137.
ZHUANG Xiaozhao LI Jianjun FU Lili CAI Qinlei. Diagnostic value of diffusion weighted imaging in local recurrence for patients with rectal carcinoma after radical resection. 中国医药导报, 2019, 16(16): 129-133,137.
2019, Vol. 16 
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