Effect of intramuscular injection of cashmere stimulating hormone combined with acupoint catgut embedding therapy on luteinizing syndrome of unruptured follicles
NIE Ying HUANG Dongmei
Maternity Care Division, Foshan Nanhai District Maternal and Child Health Hospital, Guangdong Province, Foshan 528200, China
Abstract：Objective To investigate the clinical effect of intramuscular injection of cashmere combined with acupoint catgut embedding therapy on luteinizing unruptured follicle syndrome. Methods A total of 100 cases of luteinizing unruptured follicle syndrome patients were selected from May 2017 to May 2018 in Foshan Nanhai District Maternal and Child Health Hospital of Guangdong Province, they were divided into control group and treatment group by random number table method, with 50 cases in each group. The control group received intramuscular injection of human chorionic gonadotropin (HCG) needle, and the treatment group was treated with catgut implantation at acupoint on the basis of the control group. Serum luteinizing hormone (LH), progesterone (P) and estrogenic hormone(E2) levels, blood routine, liver and kidney function were assayed before and after treatment. Results There was no significant difference in the average treatment cycle and ovulation cycle between the two groups (P ＞ 0.05). The pregnancy rate and ovulation rate in the treatment group were higher than those in the control group (P ＜ 0.05). After treatment, the serum P and LH levels of the two groups were higher than before treatment, and the serum P, LH and E2 levels of the treatment group were higher than those of the control group, the differences were statistically significant (P ＜ 0.05). Before intramuscular injection of HCG, there was no significant difference in serum P between the two groups (P ＞ 0.05). The intima thickness before intramuscular injection of HCG in the treatment group was thicker than that in the control group (P ＜ 0.05). Seven days after intramuscular injection, serum P level in the two groups were higher than those before intramuscular injection of HCG, and the treatment group was higher than that in the control group (P ＜ 0.05). After 7 days of intramuscular injection, the intima thickness of both groups were thicker than those before intramuscular injection of HCG, and the intima thickness of the treatment group was thicker than that of the control group, the difference was statistically significant (P ＜ 0.05). Conclusion Acupoint catgut embedding plus intramuscular injection HCG needle can promote ovulation by elevated serum LH levels, progesterone increase right and endometrial thickness become suitable after ovulation, thereby improving pregnancy rates in the patients with polycystic ovarian syndrome.
[1] 林兰娟.补肾活血方案治疗排卵障碍性不孕不育的临床观察[J].医药前沿，2016，6（30）：310-311.
[2] 蒋华全.针灸治疗排卵障碍性不孕症的应用与疗效评价[J].健康之路，2018，17（8）：249.
[3] 谭瑞常.针灸治疗排卵障碍性不孕症的应用及效果评估[J].临床医药文献杂志，2018，5（11）：87-88.
[4] 柳元娥.排卵障碍性不孕症应用针灸治疗的临床效果及对患者流产率的影响分析[J].实用妇科内分泌杂志，2018， 5（21）：67-68.
[5] 俞瑾，郑怀美，邴圣民.电针促排卵和血FSH、LH水平及滤泡生长的观察[J].中西医结合杂志，1998，18（40）：225.
[6] Pridd AR，Killick SR，Elstein M. The effect of prostaglandin synthetase inhibitors on human preovulatory follicular fluid prostaglandin， thromboxane， and leukotriene concentrations [M]. J Clin Endocrinol Metab，1990，71（1）：235.
[7] Tamura H，Takasaki A，Tanignchi K，et al. Changes in blood-fiow impedance of the human corpus liuteum through out the luteal phase and during early pregnancy [J]. Fertil Steril，2008，90（6）：2334-2339.
[8] 黄雪坤，冯月枝，黄永汉.麒麟丸联合人绝经期促性腺激素治疗未破裂卵泡黄素化综合征的疗效研究[J].中国现代医学杂志，2016，26（9）：114-117.
[9] Check JH. Ovulation defects despite regular menses：Part Ⅲ [J]. Clin Exp Obstet Gynecol，2007，34（3）：133-136.
[10] Zaidi J，Jurkovic D，Campbell S，et al. Luteinized unruptured follicle：morphology，endocrine function and blood flow changes during the menstrual cycle [J]. Hum Rep，1995，10（1）：44-49.
[11] Azmoodeh A，Manesh MP，Asbagh FA，et al. Effects of Letrozole-HMG and Clo-miphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial [J]. Glob J Health Sci，2016，8（4）：244-252.
[12] 蒋雪霞，陈红，王博伟.梅花针多点穴位叩刺治疗未破裂卵泡黄素化综合征临床研究[J].实用中医药杂志，2014，30（10）：896-898.
[13] 范迎迎，黄梅花.黄素化未破裂卵泡综合征中医治疗进展.[J]中日友好医院学报，2017，31（3）：190-192.
[14] 黄碧琴，何家振，张花，等.张迎春教授治疗未破裂卵泡黄素化综合征经验总结[J].浙江中医药大学学报，2016， 40（10）：750-752.
[15] 赵彩彩，郝兰枝.郝兰枝教授治疗卵泡未破裂黄素化综合征的经验总结[J].中医临床研究，2015，29（7）：55-56.
[16] 王鹭霞，柯毅凤，林雅菁，等.未破裂卵泡黄素化综合征发病机理研究进展[J].光明中医，2013，28（3）：643-645.
[17] 马建新，王旭初，张平，等.电针结合尿激酶治疗未破裂卵泡黄素化综合征疗效研究[J].河北医药，2013，35（8）：1191-1193.
[18] 李婷婷，汪翔，岳超敏，等.宫腔内注射人绒毛膜促性腺激素对反复体外受精-胚胎移植失败患者的治疗作用[J].中华临床医师杂志：电子版，2013，7（9）：3862-3865.
[19] 赵彦.针灸促排卵[J].陕西中医，2006，27（6）：663.
[20] Tarín JJ，Hamatani T，Cano A. Acute stress may induce ovulation in women [J]. Reprod Biol Endocrinol，2010，8：53.
[21] 林丽娜，常惠，袁杰.中西医治疗黄素化未破裂卵泡综合征研究进展[J].实用中医药杂志，2011，27（9）：640-642.
[22] 王利红，徐文婷.针药结合治疗未破裂卵泡黄素化综合征的临床研究[J].南京中医药大学学报，2016，32（1）：32-34.
[23] 杨晓祎，卢光琇.黄素化未破裂卵泡综合征的发生及相关治疗[J].国际病理科学与临床杂志，2009，29（2）：139-143.
2019, Vol. 16 
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