Abstract：Objective To explore the clinical application of transcutaneous acupoint electrical stimulation in improving the early recovery quality of patients after laparoscopic cholecystectomy (LC). Methods A total of 93 patients with LC admitted to Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University from January 2016 to October 2018 were selected as the study objects. They were divided into control group (46 cases) and research group (47 cases) according to random number table method. The control group was given Dexmedetomidine during LC, and the research group received transcutaneous acupoint electrical stimulation combined with Dexmedetomidine during LC. Heart rate (HR) and mean arterial pressure (MAP) were compared at before anesthesia (T1), 5 min after intubation (T2), 5 min after establishment of pneumoperitoneum (T3), 15 min after establishment of pneumoperitoneum (T4), and 5 min after operation (T5). The level of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), neuron specific enolation (NSE) and superoxide dismutase (SOD) at T1, T5 and postoperative 1 day(T6) were compared between the two groups. The postoperative delirium rating scale score, sedation score, visual analogue score (VAS) and comfort score were compared between the two groups. The occurrence of adverse reactions during treatment was recorded. Results The HR and MAP of control group at T2-T5 time point were higher than those at T1 time point (P ＜ 0.05). There was no significant difference in HR and MAP between the time points of T2-T5 and T1 in the research group (P ＞ 0.05). HR and MAP of the research group at T2-T5 time points were significantly lower than those in the control group at the same time point(P ＜ 0.05). The SOD of the two groups at T5 time point was lower than that before treatment, but the SOD of the research group was higher than that of the control group; NSE was higher than before treatment, but lower in the research group than in the control group (P ＜ 0.05). The levels of IL-6 and TNF-α at T5 and T6 time points in both groups were higher than those at T1 time point, but the levels of IL-6 and TNF-α in the research group were lower than those in the control group (P ＜ 0.05). There were no significant differences in VAS score and comfort score between the two groups (P ＞ 0.05). Postoperative delirium rating scale score in the research group was lower than that in the control group, and sedation score was higher than that in the control group (P ＜ 0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion The application of transcutaneous acupoint electrical stimulation in LC can maintain hemodynamic stability, improve the level of serum SOD, NSE, IL-6 and TNF-α, without increasing the incidence of adverse reactions, and effectively improve the early recovery quality of patients.
陆斌 王麒 丁玲玲. 经皮穴位电刺激对腹腔镜胆囊切除术患者术后早期恢复质量的影响[J]. 中国医药导报, 2019, 16(13): 112-115,119.
LU Bin WANG Qi DING Lingling. Effect of transcutaneous acupoint electrical stimulation on early recovery quality of patients after laparoscopic cholecystectomy. 中国医药导报, 2019, 16(13): 112-115,119.
2019, Vol. 16 
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